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Condurango is a tropical woody vine that can be found in the high mountain jungles and cloud forests between 2,000 and 3,000 m in elevation. It is indigenous to the lower slopes of the Andes in Peru, and is traditionally used there for all types of stomach conditions,* For more complete information about condurango (Marsdenia cundurango), please refer to the Database File for Condurango in the Tropical Plant Database. Check out the new Discussion Forums to see if anyone is talking about how they are using this natural rainforest remedy.
Traditional Uses:* for indigestion, nausea, vomiting and stomach pain; as a bitter stomach tonic to increase appetite; for gastric ulcers; as a digestive aid to increase and stimulate digestive juices and bile; for nervous eating disorders (anorexia, etc.)
Suggested Use: This plant is best prepared as an infusion (tea): Use one teaspoon of powder for each cup of water. Pour boiling water over herb in cup and allow to steep 10 minutes. Strain tea (or allow settled powder to remain in the bottom of cup) and drink warm. It is traditionally taken in 1/2 cup dosages, twice daily. For more complete instructions on preparing herbal infusions see the Methods for Preparing Herbal Remedies Page.
Contraindications: One case report was published that a patient with a known latex allergy had an allergic reaction to a condurango tea. If you are allergic to latex, it is best to avoid using this plant.
Drug Interactions: None reported.
Third-Party Published Research*
All available third-party research on condurango can be found at PubMed.
A partial listing of the published research on condurango is shown below:
Yamasaki, K., et al. "Studies on the effect of crude drugs on enzyme activites (IV) Influence of stomachic crude drugs on digestive enzymes." Shoyakugaku Zasshi. 1986; 40(3): 289-294.
Balreira, A., et al. "Uncoupling between CD1d upregulation induced by retinoic acid and conduritol-B-epoxide and iNKT cell responsiveness." Immunobiology. 2009 Aug 1.
De Las Heras, B., et al. " Antiinflammatory and antioxidant activity of plants used in traditional medicine in Ecuador." J. Ethnopharmacol. 1998; 61(2): 161-166.
Ortega, T., et al. "Anti-inflammatory activity of ethanolic extracts of plants used in traditional medicine in Ecuador." Phytother. Res. 1996: S121 -S122.
Hayashi, K., et al. "Antitumor active glycosides from condurango cortex." Chem. Pharm. Bull. 1980: 1954-1958.
Takase, M., et al. "Studies on the constituents of Asclepiadaceae plants. 49. Confirmation of the structures of antitumor-active glycosides in condurango cortex. Chemical transformation of the aglycone moiety." Chem. Pharm. Bull. 1982: 2429-2432.
Hayashi, K., et al. "Further investigation of antitumor condurangoglycosides with C-18 oxygenated aglycone." Chem. Pharm. Bull. 1981: 29(9): 2725-2730.
Anon. "Antitumor substances from Marsdenia cundurango." Patent 1981. Japan Kokai Tokkyo Koho 81 125,400.
Anon. "Condurango extracts and anti-tumor agents from same." Patent 1981 Japan Kokai Tokkyo Koho 81 147,721.
Anon. "Condurango glycoside EO1." Patent 1982 - Japan Kokai Tokkyo Koho 57 163,398
Mitsuhashi, H., et al. "Condurango glycoside compounds, processes for their preparation, antitumor agents comprising them and compositions." U.S. Patent no. 4,452,786 June 5, 1984.
Simões-Pires, C., et al. "A TLC bioautographic method for the detection of alpha- and beta-glucosidase inhibitors in plant extracts." Phytochem. Anal. 2009 Nov; 20(6): 511-5.
Wei, J., et al. "Experimental [corrected] study of hypoglycemic activity of conduritol A of stems of Gymnema sylvestre. Zhongguo. Zhong. Yao. Za. Zhi. 2008 Dec; 33(24): 2961-5.
Antimicrobial Actions (virus & bacteria):
Grange, J. M., et al. "Detection of antituberculous activity in plant extracts." J. Appl. Bacteriol. 1990; 68(6): 587-591.
May, G., et al. "Antiviral activity of aqueous extracts from medicinal plants in tissue cultures." Arzneim-Forsch. 1978: 28(1): 1-7.
* The statements contained herein have not been evaluated
by the Food and Drug Administration.
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not intended to treat, cure, mitigate or prevent any disease.
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Last updated 12-17-2012