Gervao Herb Powder - Stachytarpheta cayenensis Gerv‚o Powder

Stachytarpheta jamaicensis

This product is no longer sold by Raintree Nutrition, Inc. See the main product page for more information why. Try doing a google search for products available from other suppliers or see the rainforest products page to find other companies selling rainforest herbal supplements or rainforest plants if you want to make this rainforest formula yourself.

Gerv‚o contains flavonoids, terpenes, phenols, and steroids. Several of these plant chemicals (including verbascoside or acetoside, scutellarein, and hispidulin ) have been documented with biological activities that may help explain the plant's indigenous uses.*

For more information gerv‚o (Stachytarpheta jamaicensis), please refer to the Database File for Gerv‚o in the Tropical Plant Database. To see photographs of gerv‚o, click here. Check out the new Discussion Forums to see if anyone is talking about how they are using this natural rainforest remedy.

Traditional Uses:* for allergies and respiratory conditions (cold, flu, asthma, bronchitis, etc.); for digestive problems (indigestion, acid reflux, ulcers, constipation, dyspepsia, slow digestion); as a general pain-reliever and anti-inflammatory for various internal/external painful inflammatory disorders; to tone, balance, strengthen, protect and detoxify the liver (and as a liver bile stimulant and for chronic liver conditions); for intestinal worms and internal/external parasites

Suggested Use: This plant is best prepared as an infusion (tea). Use one teaspoon of powder for each cup of water. Pour boiling water over herb in cup and allow to steep 10 minutes. Strain tea (or allow settled powder to remain in the bottom of cup) and drink warm. It is traditionally taken in 1/2 cup amounts, twice daily. For more complete instructions on preparing herbal infusions, see the Methods for Preparing Herbal Remedies Page.

Contraindications:
  • Not to be used during pregnancy or while breast feeding.
  • Gerv‚o has lowered blood pressure in animal studies. Those with low blood pressure should use with caution.
  • Gerv‚o has demonstrated a hypoglycemic effect in animal studies. Those with diabetes or hypoglycemia should monitor their blood sugar levels closely while taking this plant.
Drug Interactions: None reported, however gerv‚o might enhance the effect of blood pressure and/or diabetes medications.





Third-Party Published Research*

All available third-party research on gervâo can be found at PubMed. A partial listing of the published third party research on gervâo is shown below:

Anti-Allergy & Bronchodilator Actions:
Lee, J., et al. "Anti-asthmatic effects of phenylpropanoid glycosides from Clerodendron trichotomum leaves and Rumex gmelini herbes in conscious guinea-pigs challenged with aerosolized ovalbumin." Phytomedicine. 2011 Jan 15;18(2-3):134-42.
Lee, J. H., et al. "The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells." Arch. Pharm. Res. 2006 Jun; 29(6): 508-13.
Hazekamp, A., et al. “Isolation of a bronchodilator flavonoid from the Thai medicinal plant Clerodendrum petasites.” J. Ethnopharmacol. 2001; 78(1): 45–9.

Digestion Stimulating, Antacid & Anti-diarrheal Actions:
Singh, N., et al. "Verbascoside isolated from Tectona grandis mediates gastric protection in rats via inhibiting proton pump activity." Fitoterapia. 2010 Oct;81(7):755-61.
Hausmann, M., et al. "In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis." Clin Exp Immunol. 2007 May;148(2):373-81.
Penido, C., et al. “Anti-inflammatory and anti-ulcerogenic properties of Stachytarpheta cayennensis (L.C. Rich) Vahl.” J. Ethnopharmacol. 2006 Mar; 104(1-2): 225-33.
Mesia-Vela, S., et al. “Pharmacological study of Stachytarpheta cayennensis Vahl in rodents.” Phytomedicine. 2004; 11(7-8): 616-24.
Vela, S. M., et al. “Inhibition of gastric acid secretion by the aqueous extract and purified extracts of Stachytarpheta cayennensis.” Planta Med. 1997; 63(1): 36–9.
Almeida, C. E., et al. “Analysis of antidiarrhoeic effect of plants used in popular medicine.” Rev. Saude. Publica. 1995; 29(6): 428–33.

Pain-Relieving, Antispasmodic & Anti-inflammatory Actions:
Isacchi, N., et al. "Antihyperalgesic activity of verbascoside in two models of neuropathic pain." J Pharm Pharmacol. 2011 Apr;63(4):594-601.
Akdemir, Z., et al. "Bioassay-guided isolation of anti-inflammatory, antinociceptive and wound healer glycosides from the flowers of Verbascum mucronatum Lam." J Ethnopharmacol. 2011 Jul 14;136(3):436-43.
Speranza, L., et al. "Antiinflammatory effects in THP-1 cells treated with verbascoside." Phytother Res. 2010 Sep;24(9):1398-404.
Yamada, P., et al. "Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells." Planta Med. 2010 Oct;76(14):1512-8.
Sulaiman, M., et al. "Antinociceptive and anti-inflammatory effects of Stachytarpheta jamaicensis (L.) Vahl (Verbenaceae) in experimental animal models." Med Princ Pract. 2009;18(4):272-9.
Speranza, L., et al. "Anti-inflammatory properties of the plant Verbascum mallophorum." J Biol Regul Homeost Agents. 2009 Jul-Sep;23(3):189-95.
Lee, J. H., et al. "The effect of acteoside on histamine release and arachidonic acid release in RBL-2H3 mast cells." Arch. Pharm. Res. 2006 Jun; 29(6): 508-13.
Penido, C., et al. “Anti-inflammatory and anti-ulcerogenic properties of Stachytarpheta cayennensis (L.C. Rich) Vahl.” J. Ethnopharmacol. 2006 Mar; 104(1-2): 225-33.
Mesia-Vela, S., et al. “Pharmacological study of Stachytarpheta cayennensis Vahl in rodents.” Phytomedicine. 2004; 11(7-8): 616-24.
Schapoval, E. E., et al. “Anti-inflammatory and antinociceptive activities of extracts and isolated compounds from Stachytarpheta cayennensis.” J. Ethnopharmacol. 1998; 60(1): 53–9.
Melita Rodriguez, S., et al. “Pharmacological and chemical evaluation of Stachytarpheta jamaicensis (Verbenaceae).” Rev. Biol. Trop. 1996 Aug; 44(2A): 353-9.
Gil, B., et al. “Effects of flavonoids on Naja Naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.” Life Sci. 1994; 54(20): PL333–38.
Feng, P. C., et al. “Pharmacological screening of some West Indian medicinal plants.” J. Pharm. Pharmacol. 1962; 14: 556–61.

Hypoglycemic Actions:
Adebajo, A., et al. "Hypoglycaemic constituents of Stachytarpheta cayennensis leaf." Planta Med. 2007 Mar;73(3):241-50.
Isah, A., et al. "The hypoglycaemic activity of the aqueous extract of Stachytarpheta angustifolia (Verbanaceae) in normoglycaemic and alloxan-induced diabetic rats." Pak J Biol Sci. 2007 Jan 1;10(1):137-41.

Liver Protective & Detoxification Actions:
Morikawa, T., et al. "Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa." Bioorg Med Chem. 2010 Mar 1;18(5):1882-90.
Park, J. C., et al. “Effects of methanol extract of Cirsium japonicum var. ussuriense and its principle, hispidulin-7-O-neohesperidoside on hepatic alcohol-metabolizing enzymes and lipid peroxidation in ethanol-treated rats.” Phytother. Res. 2004; 18(1): 19-24.
Xiong, Q., et al. “Acteoside inhibits apoptosis in D-galactosamine and lipopolysaccharide-induced liver injury.” Life Sci. 1999; 65(4): 421–30.
Xiong, Q., et al. “Hepatoprotective activity of phenylethanoids from Cistanche deserticola.” Planta Med. 1998; 64(2): 120–25.
Ferrandiz, M. L., et al. “Hispidulin protection against hepatotoxicity induced by bromobenzene in mice.” Life Sci. 1994; 55(8): PL145–50.

Kidney Protective Actions:
Hayashi, K., et al. “Acteoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent (2): Effect of acteoside on leukocyte accumulation in the glomeruli of nephritic rats.” Jpn. J. Pharmacol. 1994 Sep; 66(1): 47-52.
Hayashi, K., et al. “Acetoside, a component of Stachys sieboldii MIQ, may be a promising antinephritic agent: effect of acteoside on crescentic-type anti-GBM nephritis in rats.” Jpn. J. Pharmacol. 1994 Jun; 65(2): 143-51.

Cellular Protective & Antioxidant Actions:
Pan, W., et al. "Isolation, purification and structure identification of two phenolic glycosides from the roots of Incarvillea younghusbandii Sprague and their antioxidant activities." Yao Xue Xue Bao. 2011 Apr;46(4):422-7.
Morikawa, T., et al. "Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa." Bioorg Med Chem. 2010 Mar 1;18(5):1882-90.
Esposito, E., et al. "Protective effect of verbascoside in activated C6 glioma cells: possible molecular mechanisms." Naunyn Schmiedebergs Arch Pharmacol. 2010 Jan;381(1):93-105.
Koo, K. A., et al. "Acteoside and its aglycones protect primary cultures of rat cortical cells from glutamate-induced excitotoxicity." Life Sci. 2006 Jul 10;79(7):709-16.
Lee, K. Y., et al. "Acteoside of Callicarpa dichotoma attenuates scopolamine-induced memory impairments." Biol. Pharm. Bull. 2006; 29(1): 71-4.
Lin, L. C., et al. "The inhibitory effect of phenylpropanoid glycosides and iridoid glucosides on free radical production and beta2 integrin expression in human leucocytes." J. Pharm. Pharmacol. 2006; 58(1): 129-35.
Galvez, M., et al. "Antioxidant activity of Plantago bellardii All." Phytother. Res. 2005; 19(12): 1074-6.
Dabaghi-Barbosa, P., et al. “Hispidulin: antioxidant properties and effect on mitochondrial energy metabolism.” Free Radic. Res. 2005; 39(12): 1305-15.
Qiusheng, Z., et al. “Effects of verbascoside and luteolin on oxidative damage in brain of heroin treated mice.” Pharmazie. 2005; 60(7): 539-43.
Zhao, C., et al. "In vitro" protection of DNA from Fenton reaction by plant polyphenol verbascoside.”
Biochim. Biophys. Acta. 2005 May 25; 1723(1-3): 114-23.
Alvarez, E., et al. “Inhibitory effects of leaf extracts of Stachytarpheta jamaicensis (Verbenaceae) on the respiratory burst of rat macrophages.” Phytother. Res. 2004; 18(6): 457-62.
Liu, M.J.,et al.“The effects of verbascoside on plasma lipid peroxidation level and erythrocyte membrane fluidity during immobilization in rabbits: a time course study.” Life Sci. 2003 Jul; 73(7): 883-92.
Sheng, G. Q., et al. “Protective effect of verbascoside on 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12 cells.” Eur. J. Pharmacol. 2002; 451(2): 119–24.
Daels-Rakotoarison, D. A., et al. “Neurosedative and antioxidant activities of phenylpropanoids from Ballota nigra.” Arzneimittelforschung. 2000; 50(1): 16-23.
Sanz, M. J., et al. “Influence of a series of natural flavonoids on free radical generating systems and oxidative stress.” Xenobiotica. 1994; 24(7): 689-99.

Antimicrobial & Antimalarial Actions:
Martins, F., et al. "Verbascoside isolated from Lepechinia speciosa has inhibitory activity against HSV-1 and HSV-2 in vitro." Nat Prod Commun. 2009 Dec;4(12):1693-6.
Okokom, J., et al. "In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis." Indian J Pharmacol. 2008 Jun;40(3):111-3.
Rigano, D., et al. "Antibacterial activity of flavonoids and phenylpropanoids from Marrubium globosum ssp. libanoticum." Phytother. Res. 2006 Dec 21;
Bermejo, P., et al. “Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia.” Planta Med. 2002; 68(2): 106–10.
Didry, N., et al. “Isolation and antibacterial activity of phenylpropanoid derivatives from Ballota nigra.” J. Ethnopharmacol. 1999; 67(2): 197–202.
Chariandy, C. M., et al. “Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties.” J. Ethnopharmacol. 1999; 64(3): 265-70.

Cardiotonic Actions:
Zhou, J., et al. “Ventricular remodeling by scutellarein treatment in spontaneously hypertensive rats.” Chin. Med. J. (Engl.). 2002; 115(3): 375–77.
Pennacchio, M., et al. “Mechanism of action of verbascoside on the isolated rat heart: increases in level of prostacyclin.” Phytother. Res. 1999; 13(3): 254–55.

Anti-Estrogen Actions:
Papoutsi, Z., et al. "Acteoside and martynoside exhibit estrogenic/antiestrogenic properties." J. Steroid Biochem. Mol. Biol. 2006; 98(1): 63-71.


* The statements contained herein have not been evaluated
by the Food and Drug Administration. This product is
not intended to treat, cure, mitigate or prevent any disease.
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Last updated 12-17-2012