Iporuru Powder - Alchornea castaneifolia - Iporuru Powder - Alchornea castaneifolia - Iporuru Powder - Alchornea castaneifolia - Iporuru Powder - Alchornea castaneifolia - Iporuru Powder - Alchornea castaneifolia Iporuru Powder

Alchornea castaneifolia

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Throughout the Amazon the bark or leaves are tinctured (generally with the local rum, called aguardiente) as a local remedy for rheumatism, arthritis, colds, and muscle pains.* It is well known to the indigenous peoples of Peru for relieving the symptoms of osteoarthritis, and in aiding flexibility and range of motion.* For more information iporuru (Alchornea castaneifolia), please refer to the Database File for Iporuru in the Tropical Plant Database. To see pictures of iporuru, click here. Check out the new Discussion Forums to see if anyone is talking about how they are using this natural rainforest remedy.

Traditional Uses:* for arthritis and rheumatism; as an internal and external anti-inflammatory and pain-reliever for muscle and joint injuries; for fungal and viral infections; for erectile dysfunction and female fertility

Suggested Use: This plant is best prepared as an infusion (tea): Use one teaspoon of powder for each cup of water. Pour boiling water over herb in cup and allow to steep 10 minutes. Strain tea (or allow settled powder to remain in the bottom of cup) and drink warm. It is traditionally taken in 1/2 cup amounts, 2-3 times daily. For more complete instructions on preparing herbal infusions, see the Methods for Preparing Herbal Remedies Page.

Contraindications: None known.

Drug Interactions: None reported.





Third-Party Published Research*

All available third-party research on iporuru can be found at PubMed. A partial listing of the published research on iporuru is shown below:

Anti-inflammatory, Antispasmodic & Pain-Relieving Actions:
Okoye, F., et al. "Topical anti-inflammatory constituents of lipophilic leaf fractions of Alchornea floribunda and Alchornea cordifolia." Nat Prod Res. 2011 Dec;25(20):1941-9.
Lopes, F., et al. "Anti-inflammatory activity of Alchornea triplinervia ethyl acetate fraction: inhibition of Hv(2)Ov(2), NO and TNF-?." Pharm Biol. 2010 Dec;48(12):1320-7.
Kouakou-Siransy, G., et al. "Effects of Alchornea cordifolia on elastase and superoxide anion produced by human neutrophils." Pharm Biol. 2010 Feb;48(2):128-33. Okoye, F., et al. "Anti-inflammatory and membrane-stabilizing stigmastane steroids from Alchornea floribunda leaves." Planta Med. 2010 Feb;76(2):172-7.
Manga, H., et al. "Anti-inflammatory compounds from leaves and root bark of Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg." J Ethnopharmacol. 2008 Jan 4;115(1):25-9.
Manga, H.M., et al. “In vivo anti-inflammatory activity of Alchornea cordifolia (Schumach. & Thonn.) Mull. Arg. (Euphorbiaceae).” J. Ethnopharmacol. 2004 Jun; 92(2-3): 209-14.
Osadebe, P. O., et al. “Anti-inflammatory effects of crude methanolic extract and fractions of Alchornea cordifolia leaves.” J. Ethnopharmacol. 2003 Nov; 89(1):19-24.
Tona, L., et al. “Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo.” Phytomedicine. 2000 Mar; 7(1): 31-8.
Dunstan, C. A., et al. “Evaluation of some Samoan and Peruvian medicinal plants by prostaglandin biosynthesis and rat ear oedema assays.” J. Ethnopharmacol. 1997; 57: 35–56.
Ogungbamila, F. O., et al. “Smooth muscle–relaxing flavonoids from Alchornea cordifolia.” Acta Pharm. Nord. 1990; 2(6): 421–22.
Persinos-Perdue, G., et al. “Evaluation of Peruvian folk medicine by the natural products research laboratories.” Abstra. Joint Meeting American Society of Pharmacognosy and Society for Economic Botany, Boston, 1981; (5) 13

Anti-ulcer and Anti-diarrhea Actions:
Lima, Z., et al. "Brazilian medicinal plant acts on prostaglandin level and Helicobacter pylori." J Med Food. 2008 Dec;11(4):701-8.
Hiruma-Lima, C. A., et al. “Antiulcerogenic activity of Alchornea castaneifolia: Effects on somatostatin, gastrin and prostaglandin.” J. Ethnopharmacol. 2006 Mar; 104(1-2): 215-24.
Agbor, G. A., et al. “The antidiarrhoeal activity of Alchornea cordifolia leaf extract.” Phytother. Res. 2004; 18(11): 873-6.
Tona, L., et al. “Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo.” Phytomedicine. 2000 Mar; 7(1): 31-8.
Tona, L., et al. “Biological screening of traditional preparations from some medicinal plants used as antidiarrhoeal in Kinshasa, Congo.” Phytomedicine. 1999 Mar; 6(1): 59-66.

Cellular Protective & Antioxidant Actions:
Osadebe, P., et al. "Phytochemical analysis, hepatoprotective and antioxidant activity of Alchornea cordifolia methanol leaf extract on carbon tetrachloride-induced hepatic damage in rats." Asian Pac J Trop Med. 2012 Apr;5(4):289-93.
Kouakou-Siransy, G., et al. "Effects of Alchornea cordifolia on elastase and superoxide anion produced by human neutrophils." Pharm Biol. 2010 Feb;48(2):128-33.
Olaleye, M., et al. "Acetaminophen-induced liver damage in mice: effects of some medicinal plants on the oxidative defense system." Exp Toxicol Pathol. 2008 Mar;59(5):319-27.
Mpiana, P. T., et al. "In vitro antidrepanocytary actvity (anti-sickle cell anemia) of some Congolese plants." Phytomedicine. 2006 Nov 16;

Antimicrobal & Antimalarial Actions:
Calvo, T., et al. "Phenolic compounds in leaves of Alchornea triplinervia: anatomical localization, mutagenicity, and antibacterial activity." Nat Prod Commun. 2010 Aug;5(8):1225-32 .
Lima, Z., et al. "Brazilian medicinal plant acts on prostaglandin level and Helicobacter pylori." J Med Food. 2008 Dec;11(4):701-8.
Igbeneghu, O. A., et al. "A study of the in vivo activity of the leaf extract of Alchornea cordifolia against multiply antibiotic resistant S. aureus isolate in mice." Phytother. Res. 2007; 21(1): 67-71.
Igbeneghu, O., et al. "A study of the In Vivo activity of the leaf extract of Alchornea cordifolia against multiply antibiotic resistant S. aureus isolate in mice." Phytother Res. 2007 Jan;21(1):67-71.
Ayisi, N. K., et al. “Comparative in vitro effects of AZT and extracts of Ocimum gratissimum, Ficus polita, Clausena anisata, Alchornea cordifolia, and Elaeophorbia drupifera against HIV-1 and HIV-2 infections.” Antiviral Res. 2003 Mar; 58(1): 25-33.
Banzouzi, J. T., et al. “In vitro antiplasmodial activity of extracts of Alchornea cordifolia and identification of an active constituent: ellagic acid.” J. Ethnopharmacol. 2002 Aug; 81(3): 399-401.
Abo, K. A., et al. “Antimicrobial screening of Bridelia micrantha, Alchormea cordifolia and Boerhavia diffusa.” Afr. J. Med. Med. Sci. 1999 Sep-Dec; 28(3-4): 167-9.
Ebi, G. C. “Antimicrobial activities of Alchornea cordifolia.” Fitoterapia. 2001; 72(1): 69-72.
Tona, L., et al. “Antiamoebic and spasmolytic activities of extracts from some antidiarrhoeal traditional preparations used in Kinshasa, Congo.” Phytomedicine. 2000 Mar; 7(1): 31-8.
Okeke, I. N., et al.” Antimicrobial spectrum of Alchornea cordifolia leaf extract.” Phytother. Res. 1999 Feb; 13(1): 67-9.
Macrae, W. D., et al. “Studies on the pharmacological activity of Amazonian Euphorbiaceae.” J. Ethnopharmacol. 1988; 22(2): 143–72.


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by the Food and Drug Administration. This product is
not intended to treat, cure, mitigate or prevent any disease.
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Last updated 1-8-2013