In Peruvian herbal medicine, clavo huasca is widely regarded as an libido booster for women.* It is an ingredient in two famous formulas for which are widely sold in the herbal markets and stores in Peru for sexual potency; one called Siete raices (Seven Roots) and the other is Rompe Calzon (Bust your Britches).* For more information about clavo huasca vine (Tynanthus panurensis), please refer to the Database File for Clavo huasca in the Tropical Plant Database. To see pictures of clavo huasca click here.

Traditional Uses:* as a female aphrodisiac for pre-menopausal women; for muscle pain and aches; as a digestive aid to calm the stomach, increase appetite, and expel intestinal gas; as a male aphrodisiac and for erectile function; as a general tonic (tones, balances, strengthens overall body functions)

Suggested Use: Take 1 to 2 grams twice daily or as desired.

Contraindications: Not to be used during pregnancy or while breast-feeding.

Drug Interactions: None reported.

Other Observations: Some women have reported becoming too sexually aggressive on clavo huasca with continued daily use. If this occurs reduce usage to 2-3 times weekly.

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Published Research on Clavo Huasca

All available third-party research on clavo huasca can be found at PubMed. A partial listing of the published research on clavo huasca updated through Feb-2019 is shown below:

Phosphodiesterase-5 Inhibitor (Erectile Function) & Aphrodisiac Actions:
Schmeda-Hirschmann, G., et al. "Male sexual enhancers from the Peruvian Amazon." J. Ethnopharmacol. 2019 Jan; 229: 167-179.
Cansian, F., et al. "Aphrodisiac properties of Tynanthus micranthus Corr. & Mello ex. Schum in male mice." Afr. J. Pharm. Pharmacol. 2014 Dec; 8(47): 1200-1204.
Singh, R., et al. "Sexual Dysfunction: An overview and medicinal plants used for treatment of sexual dysfunction." Crit. Rev. Pharm. Sci. 2012; 1(2): 9-24.
Singh, R., et al. "Overview on traditional medicinal plants as aphrodisiac agent." J. Pharmacog. Phytochem. 2012; 1(4): 43-56.
Wani, B., et al. "Plants as Repository of Aphrodisiacs." J. Pharm. Res. 2011; 4(11): 3882-3887.
Singh, B., et al. "Pharmacological potential of plants used as aphrodisiacs." Int. J. Pharm. Sci. Rev. Res. 2010 Dec; 5(1): 104-113.

Anti-inflammatory Actions:
Cansian, F., et al. "Chemical review and studies related to species from the genus Tynanthus (Bignoniaceae)." Braz. J. Pharm. Sci. 2015 Jul/Sep; 51(3): 515-523.
Pesce, M., et al. "Verbascoside down-regulates some pro-inflammatory signal transduction pathways by increasing the activity of tyrosine phosphatase SHP-1 in the U937 cell line." J. Cell. Mol. Med. 2015 Jul; 19(7): 1548-56.
Gao, H., et al. "Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization."Br. J. Pharmacol. 2017 Sep; 174(17): 2880-2896.
Morales, L., et al. "Bioactive properties of Tynanthus panurensis (Bureau) Sanwith bark extract, the Amazonian "clavo huasca"." J. Med. Food. 2011 Sep; 14(9): 939-43.

Antioxidant Actions:
Wang, Y., et al. "Inhibitory effect of verbascoside on xanthine oxidase activity." Int. J. Biol. Macromol. 2016 Dec; 93(Pt A): 609-614
Morales, L., et al. "Bioactive properties of Tynanthus panurensis (Bureau) Sanwith bark extract, the Amazonian "clavo huasca"." J. Med. Food. 2011 Sep; 14(9): 939-43.
Chavez, L., et al. “[Phytochemical screening of flavonoids in Clavo Huasca (Tynanthus polyanthus. Sandwith Bureau) in the location of San Bernardo, Tambopata, Madre de Dios, Peru].” Rev. Cient. Biodiv. Amaz. 2011; 3(3): 10-17.
Nagababu, E., et al. "Assessment of antioxidant activity of eugenol in vitro and in vivo." Methods Mol. Biol. 2010; 610: 165-80.
Kar Mahapatra, S., et al. "Eugenol protects nicotine-induced superoxide mediated oxidative damage in murine peritoneal macrophages in vitro." Eur. J. Pharmacol. 2009 Nov; 623(1-3): 132-40.
Slamenova, D., et al. "Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines." Mutat. Res. 2009 Jun-Jul; 677(1-2): 46-52.
Plaza, A., et al. "Phenylpropanoid glycosides from Tynanthus panurensis: characterization and LC-MS quantitative analysis." J. Agric. Food Chem. 2005 Apr; 53(8): 2853-8.

Anti-Diabetic Actions:
Ferrier J., et al. "Traditional medicines used by Q'eqchi' Maya to treat diabetic symptoms and their antiglycation potential."J. Ethnopharmacol. 2018 Oct 5; 224: 504-511.

Enhanced Spermatogenesis Actions:
Melo, F., et al. "The effects of Tynnanthus fasciculatus (Bignoniaceae) infusion on testicular parenchyma of adult Wistar rats." Biol. Res. 2010; 43(4): 445-50.