Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Azadirachta indica A. JUSS. (Meliaceae) -- Neem


Chemicals

1-TIGLOYL-3-ACETYL-11-METHOXY-AZADIRACHTININ Bark: DUKE1992A
No activity reported.

17-BETA-HYDROXYAZADIRDIONE Seed: DUKE1992A
No activity reported.

17-EPIAZADIRADIONE Seed: DUKE1992A
No activity reported.

1ALPHA-METHOXY-1,2-DIHYDROAZADIRADIONE Seed: DUKE1992A
No activity reported.

1BETA,2BETA-DIEPOXY-AZADIRADIONE Seed: DUKE1992A
No activity reported.

22,23-DIHYDRO-23BETA-METHOXY-AZADIRACHTIN Seed: DUKE1992A
No activity reported.

3-ACETYL-7-TIGLOYL-LACTONE-VILASININ Leaf: DUKE1992A
No activity reported.

3-DESACETYL-3-CINNAMOYL-AZADIRACHTIN Leaf: DUKE1992A
No activity reported.

3-DESACETYL-SALANIN Leaf: DUKE1992A
No activity reported.

3-DESACETYLSALANNIN Seed: DUKE1992A
No activity reported.

3-TIGLOYLAZADIRACHLOL Seed: DUKE1992A
No activity reported.

4-EPINIMBIN Seed: DUKE1992A
No activity reported.

4ALPHA,6ALPHA-DIHYDROXY-A-HOMO-AZADIRADIONE Leaf: DUKE1992A
No activity reported.

6-ACETYL-NIMBANDIOL Seed: DUKE1992A
No activity reported.

6-DESACETYLNIMBINENE Bark: DUKE1992A Leaf: DUKE1992A Seed: DUKE1992A
No activity reported.

6-O-ACETYL-NIMBANDIOL Plant: DUKE1992A
Antifeedant IC50=4.4 ppm diet 438 ; Pesticide DUKE1992B

7-ACETYLNEOTRICHILENONE Seed: DUKE1992A
No activity reported.

7-DESACETYL-7-BENZOYL-AZADIRADIONE Seed: DUKE1992A
No activity reported.

7-DESACETYL-7-BENZOYLEPOXY-AZADIRADIONE Seed: DUKE1992A
No activity reported.

7-DESACETYL-7-HYDROXY-AZADIRADIONE Fruit: DUKE1992A
No activity reported.

7-DESACETYL-GEDUNIN Seed: DUKE1992A
No activity reported.

ARACHIDIC-ACID Fruit 9,360 ppm; DUKE1992A
No activity reported.

ASH Fruit 39,000 ppm; DUKE1992A Leaf 112,000 ppm; DUKE1992A
No activity reported.

AZADIRACHTANIN Leaf: DUKE1992A
No activity reported.

AZADIRACHTANIN-A Leaf: DUKE1992A
No activity reported.

AZADIRACHTIN Seed: DUKE1992A
Antiecdysic 1 ppm DUKE1992B ; Antifeedant IC50=0.07-0.7 ppm diet; Antitrypanosomic NIG ; Insecticide NIG ; Insectifuge 382 ; Nematistat 10 ug/ml NIG ; Pesticide DUKE1992B

AZADIRACHTOL Fruit: DUKE1992A
No activity reported.

AZADIRADIONE Seed: DUKE1992A
Antimalarial IC50=3 ug/ml ABS1

AZADIRONE Seed: DUKE1992A
Antimalarial IC50=12 ug/ml ABS1

BEHENIC-ACID Fruit 2,385 ppm; DUKE1992A
Cosmetic JBH

BETA-SITOSTEROL Flower: DUKE1992A Leaf: DUKE1992A
Androgenic DUKE1992B ; Anorexic MAR ; Antiadenomic M11 ; Antiandrogenic JE28:221 ; Antibacterial QJC28:155 ; Anticancer (Breast) PS131:95 ; Antiedemic IC54=320 mg/kg orl DFN:160 ; Antiestrogenic JE28:221 ; Antifeedant 382 ; Antifertility JE28:221 ; Antigonadotrophic JE28:221 ; Antihyperlipoproteinaemic JBH ; Antiinflammatory; Antileukemic PJB1(2):287 ; Antilymphomic PJB1(2):287 ; Antimutagenic 250 ug/mL JAFC37:1365 ; Antiophidic 2.3 mg mus EMP5:363 ; Antiprogestational JE28:221 ; Antiprostaglandin 30 mg/day/12 wks FT68(4):291 ; Antiprostatadenomic M11 ; Antiprostatitic 10-20 mg/3 x/day/orl man; Antitumor (Breast) PS131:95 ; Antitumor (Cervix) PJB1(2):287 ; Antitumor (Lung) PJB1(2):287 ; Antiviral PS75:161 ; Artemicide LC50=110 ppm PC29(5):1667 ; Cancer-Preventive 525 ; Candidicide QJC28:155 ; Estrogenic DUKE1992B ; Gonadotrophic JE28:221 ; Hepatoprotective PMP23:60 ; Hypocholesterolemic 2-6 g/man/day/orl M30 9-3,330 mg/man/day/orl MAR ; Hypoglycemic JE27:243 ; Hypolipidemic 2-6 g/day; Pesticide DUKE1992B ; Spermicide JE28:221 ; Ubiquiot JBH ; Ulcerogenic 500 mg/kg ipr rat FT63(1):3

CALCIUM Fruit 1,381 - 3,400 ppm DUKE1992A Leaf 16,700 - 26,500 ppm DUKE1992A
Antiallergic 500 mg/day; Antianxiety DAS ; Antiatherosclerotic WER ; Antidepressant DAS ; Antidote (Aluminum) DAS ; Antidote (Lead) DAS ; Antihyperkinetic DAS ; Antiinsomniac DAS ; Antiosteoporotic 500 mg day WER ; Antiperiodontitic 750 mg day WER ; AntiPMS 1 g day WER ; Antitic DAS ; Hypocholesterolemic 500 mg day WER ; Hypotensive 1 g/day WER

CARBOHYDRATES Fruit 834,000 ppm; DUKE1992A Leaf 692,000 ppm; DUKE1992A
No activity reported.

DESACETYLNIMBIN Stem Bark: DUKE1992A
No activity reported.

EO Stem Bark 200 ppm; DUKE1992A
No activity reported.

EPOXYAZADIRADIONE Seed: DUKE1992A
No activity reported.

FAT Fruit 55,000 ppm; DUKE1992A Seed 450,000 ppm; DUKE1992A
No activity reported.

FIBER Leaf 127,000 ppm; DUKE1992A
Antidiabetic DUKE1992B ; Antiobesity DUKE1992B ; Antitumor PAM ; Antiulcer PAM ; Cancer-Preventive 525 ; Cardioprotective DUKE1992B ; Hypocholesterolemic DUKE1992B ; Hypotensive 10 g/man/day/orl PAM ; Laxative DUKE1992B

GEDUNIN Seed: DUKE1992A
Antimalarial IC50=0.3-1 uM JNP52:922 IC50=50 ug/mL PR4:33 IC50=8.5 ug/ml JE15:204 ; Cytotoxic ED50=275.1 ug/mL PR4(1):34

HYPEROSIDE Leaf: DUKE1992A
Antibacterial MIC=250-500 ug/ml PM57:A43 ; Anticapillary-Fragility TOX ; Antidermatitic DUKE1992B ; Antiflu AYL ; Antihepatotoxic TOX ; Antiinflammatory 1/4 indomethacin PM57:A131 ; Antioxidant PC33:557 ; Antiviral; cAMP-Inhibitor IC50=0.14 mg/ml PM57:A133 ; Cancer-Preventive 525 ; Capillarifortificant JBH ; Capillarigenic JBH ; Diuretic DUKE1992B ; Hypotensive ivn dog HG22:31 ; Pesticide DUKE1992B

ISOAZADIROLIDE Leaf: DUKE1992A
No activity reported.

ISOMARGOSINOLIDE Plant: DUKE1992A
No activity reported.

ISONIMBINOCINOLIDE Plant: DUKE1992A
No activity reported.

ISONIMBINOLIDE Stem Bark: DUKE1992A
Pesticide DUKE1992B

ISONIMBOCINOLIDE Leaf: DUKE1992A
No activity reported.

ISONIMOLICINOLIDE Fruit: DUKE1992A
No activity reported.

KAEMPFEROL Flower 2,000 ppm; DUKE1992A
11B-HSD-Inhibitor CPT59:62 ; 5-Lipoxygenase-Inhibitor IC50 (uM)=20; Aldose-Reductase-Inhibitor 100 uM JBC8:211 ; Antiaggregant 30 uM; Antiallergic RWG122 ; Antibacterial 20 ug/ml; Anticancer JAF47:397 ; Antifertility 250 mg/kg day/60 days/orl rat PMP23:193 ; Antigingivitic 20 ug/ml JNP59:987 ; Antihistaminic 411 ; Antiimplantation JE32:175 ; Antiinflammatory 20 mg/kg DUKE1992B 200 mg/kg ipr rat DUKE1992B ; Antileukemic IC50=3.1 ug/ml LS55:1061 ; Antilymphocytic JBH ; Antimutagenic ID50=10-40 nM PCF ; Antioxidant IC50=40 uM PC27:972 ; Antiperiodontic 20 ug/ml JNP59:987 ; Antiplaque JNP59:987 ; Antiradicular 7 x quercetin; Antiseptic 20 ug/ml JNP59:987 ; Antiserotonin 200 mg/kg ipr rat FT63(1):3 ; Antispasmodic 411 ; Antitumor JAF47:397 ; Antitumor-Promoter CPB38:774 ; Antiulcer 50-200 mg/kg ipr rat; Antiviral; Apoptotic 60 uM PMID10673981 ; Aromatase-Inhibitor IC12=1 uM/l JMF2:235 ; cAMP-Phosphodiesterase-Inhibitor AFR27:180 ; Cancer-Preventive 525 ; Carcinogenic ZUL ; Choleretic LAF ; COX-2-Inhibitor COX:50 ; Cyclooxygenase-Inhibitor IC50 (uM) =20; Diaphoretic? LRN-DEC90 ; Diuretic BJP3:10 ; Estrogenic EC50=0.1-25 uM/l JMF2:227 EC50=0.56 uM PMID10923837 ; HIV-RT-Inhibitor IC50=50-150 ug/ml JNP54:142 ; Hypotensive FT1990:508 ; Inotropic PMID10404425 ; Iodothyronine-Deiodinase-Inhibitor JBH ; Lipoxygenase-Inhibitor JBH ; MAO-Inhibitor PMID10813558 ; Mutagenic JBH ; Natriuretic BJP3:10 ; Neuroprotective PMID10813558 ; PAF-Inhibitor FT67:548 ; Pesticide DUKE1992B ; Protisticide PR13:102 ; Quinone-Reductase-Inducer 3 uM; Teratologic DUKE1992B ; Topoisomerase-I-Inhibitor TIH14:223 ; Topoisomerase-II-Inhibitor IC50=8.1 ug/ml JNP58:217 ; Uterotrophic EC50=0.1-25 uM/l JMF2:227 ; Vasodilator JAFC48:220

LIGNOCERIC-ACID Fruit 1,125 ppm; DUKE1992A
Antihepatotoxic

LINOLEIC-ACID Fruit 47,250 ppm; DUKE1992A
5-Alpha-Reductase-Inhibitor PMID10830511 ; Antianaphylactic EMP6:189 ; Antiarteriosclerotic JE26:80 ; Antiarthritic EMP6:189 ; Anticoronary JBH ; Antieczemic EMP6:189 ; Antifibrinolytic EMP1:53 ; Antigranular DUKE1992B ; Antihistaminic EMP6:189 ; Antiinflammatory IC50=31 uM; Antileukotriene-D4 POP:153 ; Antimenorrhagic PAM ; AntiMS EMP6:189 ; Antiprostatitic PAM ; Cancer-Preventive 525 ; Carcinogenic SN146:421 ; Hepatoprotective DUKE1992B ; Hypocholesterolemic GAS ; Immunomodulator EMP6:189 ; Insectifuge 382 ; Metastatic SN146:421 ; Nematicide NIG

MAGNESIUM Fruit 4,000 ppm; DUKE1992A Leaf 7,100 ppm; DUKE1992A
Antiaggregant 400 mg/day; Antianginal WER ; Antianorectic DAS ; Antianxiety WER ; Antiarrhythmic; Antiarthritic DAS ; Antiasthmatic PAM ; Antiatherosclerotic; Anticonvulsant FAC ; Anticoronary SYN-X ; Antidepressant DAS ; Antidiabetic 400-800 mg/man/day; Antidysmenorrheic 100 mg 4 x day WER ; Antiepileptic 450 mg/day; Antiglaucomic ABEL1999 ; Antihyperkinetic DAS ; Antihypoglycemic DAS ; Antiinflammatory 100 mg 4 x day WER ; Antiinsomniac DAS ; Antilithic PAM ; Antimastalgic PAM ; Antimigraine 200 mg/day WER ; Antineurotic DAS ; Antiosteoporotic 500-1,000 mg/day/wmn/orl; AntiPMS 400-800 mg/day/wmn/orl; Antiretinopathic 400 mg/day SYN-X ; Antispasmophilic 500 mg/day WER ; Antistroke 400 mg/day SYN-X ; Antisyndrome-X 400 mg/man/day SYN-X ; Calcium-Antagonist RWG125 ; CNS-Depressant FAC ; Hypocholesterolemic 400 mg/day WER ; Hypotensive 260-500 mg/day; Insulinogenic 400 mg/day SYN-X ; Myorelaxant 100 mg 4 x day WER ; Uterorelaxant WER ; Vasodilator WER

MARGODUNOLIDE Plant: DUKE1992A
No activity reported.

MARGOSINE Stem Bark: DUKE1992A
No activity reported.

MARGOSINOLIDE Plant: DUKE1992A
No activity reported.

MELDENIN Seed: DUKE1992A
No activity reported.

MELIANTRIOL Seed: DUKE1992A
Antifeedant RAA ; Insectifuge 382 ; Pesticide DUKE1992B

MYRICETIN Flower 1,000 ppm; DUKE1992A
Allelochemic IC82=1 mM 438 ; Antiallergenic RWG122 ; Antibacterial MIC=20-500 ug/ml; Antifeedant IC52=<1,000 ppm diet 438 ; Antigastric DUKE1992B ; Antigingivitic MIC=20 ug/ml JNP59:987 ; Antigonadotrophic JBH ; Antihistaminic RWG122 ; AntiHIV POP:270 ; Antiinflammatory OMM ; Antimutagenic ID50=2-5 nM PCF ; Antioxidant 1.4 uM P&T78:143 IC99=200 ppm PCF ; Antiperiodontic MIC=20 ug/ml JNP59:987 ; Antiplaque JNP59:987 ; Antiseptic JNP59:987 ; Antiviral POP:270 ; Apoptotic 60 uM PMID10673981 ; Cancer-Preventive 525 ; Candidicide MIC=150 ug/ml PM57:A43 ; COMP-Inhibitor JCN70:1040 ; Diuretic OMM ; Hypoglycemic EMP6:170 ; Larvistat IC50=2.6-3.5 mM/kg diet 438 ; Lipoxygenase-Inhibitor JBH ; Mutagenic NIG ; Oxidase-Inhibitor JBH ; Pesticide DUKE1992B ; Quinone-Reductase-Inducer 36 uM CLE120:213 ; Topoisomerase-I-Inhibitor IC50=11.9 ug/ml; Topoisomerase-II-Inhibitor; Tyrosine-Kinase-Inhibitor EMP6:170 ; Vasodilator JAFC48:220

MYRISTIC-ACID Fruit 630 ppm; DUKE1992A
Cancer-Preventive 525 ; Cosmetic JBH ; Hypercholesterolemic GAS ; Lubricant JBH ; Nematicide NIG

NIMBAFLAVONE Leaf: DUKE1992A
No activity reported.

NIMBANDIOL Leaf: DUKE1992A Stem: DUKE1992A
No activity reported.

NIMBIDIN Seed: DUKE1992A Stem Bark 4,000 ppm; DUKE1992A
Amebicide 2,000 ppm AAK ; Analgesic PM2:143 ; Antiarthritic PM2:143 ; Antibacterial PM2:143 ; Anticholinergic AAK ; Antidermatitic AAK ; Antieczemic AAK ; Antieosinophilic AAK ; Antifuruncular AAK ; Antigingirrhagic AAK ; Antiherpetic DUKE1992B ; Antihistaminic 80 mg/kg PM2:145 ; Antiinflammatory PM2:143 ; Antipyorrheic AAK ; Antipyretic PM2:143 ; Antiscabic AAK ; Antiseborrheic AAK ; Antitubercular AAK ; Antiulcer ED=20-40 ppm orl rat PM2:143 ; CNS-Sedative >250 mg/kg orl mus PM2:146 ; CNS-Stimulant DUKE1992B ; Depressant DUKE1992B ; Diuretic PM2:143 ; Fungicide AAK ; Hypoglycemic PM2:143 ; Paramecicide 2,000 ppm DUKE1992B ; Pesticide DUKE1992B ; Protisticide DUKE1992B

NIMBIN Stem Bark 400 ppm; DUKE1992A
Antiallergic 1mg/ml AAK ; Antihistaminic AAK ; Antimalarial IC50=50 ug/mL PR4(1):33 ; Fungicide AAK ; Pesticide DUKE1992B ; Spermicide DUKE1992B

NIMBINENE Bark: DUKE1992A Leaf: DUKE1992A Stem: DUKE1992A
No activity reported.

NIMBININ Stem Bark 10 ppm; DUKE1992A
Antiarthritic DUKE1992B ; Antimalarial IC50=0.77 ug/mL PR4(1):33 ; Antiulcer 20-40 DUKE1992B ; Cytotoxic ED50=7.13 ug/mL PR4(1):34 ; Pesticide DUKE1992B

NIMBINONE Stem Bark: DUKE1992A
No activity reported.

NIMBIOL Bark: DUKE1992A
No activity reported.

NIMBIONE Stem Bark: DUKE1992A
No activity reported.

NIMBOCINOLIDE Plant: DUKE1992A
No activity reported.

NIMBOCINOME Plant: DUKE1992A
No activity reported.

NIMBOLIDE Leaf: DUKE1992A
Antimalarial IC50=1.74 ug/mL PR4(1):33 ; Cytotoxic ED50=10.14 ug/mL PR4(1):34 ; Pesticide DUKE1992B

NIMBOLIN-A Wood: DUKE1992A
No activity reported.

NIMBOLIN-B Wood: DUKE1992A
No activity reported.

NIMBOSTEROL Stem Bark 300 ppm; DUKE1992A
No activity reported.

NIMOCINOL Fruit: DUKE1992A
No activity reported.

NIMOLICINOIC-ACID Fruit: DUKE1992A
No activity reported.

NIMOLICINOL Seed: DUKE1992A
No activity reported.

NIMOLINONE Fruit: DUKE1992A
No activity reported.

NONACOSANE Flower: DUKE1992A
Antimutagenic 250 ug/mL JAF37:1364.1989 ; Antiviral PS75:161

OLEIC-ACID Fruit 238,050 ppm; DUKE1992A
5-Alpha-Reductase-Inhibitor PMID10830511 ; Allergenic M&R495 ; Anemiagenic DUKE1992B ; Antiinflammatory IC50=21 uM POP:153 ; Antileukotriene-D4 POP:153 ; Cancer-Preventive 525 ; Choleretic 5 ml/man DUKE1992B ; Dermatitigenic M&R495 ; FLavor FEMA 1-30 ARC ; Hypocholesterolemic GAS ; Insectifuge 382 ; Irritant M11 ; Percutaneostimulant CPB38:3086 ; Perfumery ARC

PALMITIC-ACID Fruit 63,000 - 71,550 ppm DUKE1992A
5-Alpha-Reductase-Inhibitor PMID10830511 ; Antifibrinolytic EMP1:53 ; FLavor FEMA 1 ARC ; Hemolytic BIS ; Hypercholesterolemic GAS ; Lubricant JBH ; Nematicide NIG ; Pesticide DUKE1992B ; Soap JBH

PHOSPHORUS Fruit 2,265 - 2,400 ppm DUKE1992A Leaf 1,900 - 2,400 ppm DUKE1992A
Antiosteoporotic DAS ; Immunostimulant DAS ; Osteogenic DAS

PROTEIN Fruit 72,000 ppm; DUKE1992A Leaf 154,000 ppm; DUKE1992A
No activity reported.

QUERCETIN Flower 1,000 ppm; DUKE1992A Leaf: DUKE1992A
11B-HSD-Inhibitor CPT59:62 ; 5-Lipoxygenase-Inhibitor IC50 (uM)=4; Aldose-Reductase-Inhibitor 100 uM 4 ug/ml SKN43:99 IC50=0.344 uM ZZZ18:623 IC50=0.84 ug/ml cow CPB43:1385 ; Allelochemic IC82=1 mM 438 ; Allergenic JBH ; Analgesic FT63(3):197 ; Antiaggregant 30 uM JAF45:4505 IC50=55 uM EMP5:333 ; Antiallergic IC50=14 uM JIM127:546 ; Antianaphylactic PR4(5):201 ; Antiasthmatic; Antiatherosclerotic PMID11020457 ; Antibacterial JBH ; Anticarcinomic (Breast) IC50=1.5 uM MED ; Anticariogenic ID50=120 ug/ml JAF48:5666 ; Anticataract PM56(3):258 ; Anticolitic 400 mg/man/3x/day PAM ; AntiCrohn's PAM ; Antidermatitic PAM ; Antidiabetic; Antielastase IC50=0.8 ug/ml DUKE1992B ; Antiencephalitic EMP5:199 ; Antiescherichic PMID10857921 ; Antiestrogenic; Antifeedant IC52=<1,000 ppm diet 438 ; Antifibrosarcomic JAF45:4505 ; Antiflu V&D ; Antigastric RR21:85 ; Antigonadotropic JBH ; AntiGTF ID50=120 ug/ml JAF48:5666 ; Antihepatotoxic PM56(2):171 ; Antiherpetic PAM ; Antihistaminic IC50=<10 uM; AntiHIV JNP60(9):884 ; Antihydrophobic V&D ; Antihypertensive KCH ; Antiinflammatory (20 mg/kg) 150 mg/kg FT5:1990 ; Antileukemic 5.5-60 uM BO2 IC50=10 uM EMP5:225 IC50=>10 ug/ml LS55:1061 ; Antileukotriene PAM ; Antilipoperoxidant IC67=50; Antimalarial IC50=1-6.4 ug/ml MPT ; Antimelanomic; Antimutagenic ID50=2-5 nM PCF ; Antimyocarditic EMP5:199 ; Antinitrosaminic PAL:339 ; Antioxidant 4.7 x Vit. E BO2 ED50=2.3 uM PR14:93 IC96=300 ppm PCF ; Antipancreatitic JNU ; Antiperiodontal PAM ; Antipermeability DUKE1992B ; Antiperoxidant PM57:A110 ; Antipharyngitic PAM ; Antiplaque PAM ; AntiPMS 500 mg/2x/day/wmn PAM ; Antipodriac PAM ; Antipolio PAM ; Antiproliferant JNM7:51 ; Antiprostanoid PCF:51 ; Antiprostatitic JNU ; Antipsoriac PAM ; Antiradicular IC50=4.6 uM PM56(6):695 ; Antispasmodic; Antistreptococcic ID50=120 ug/ml JAF48:5666 ; Antithiamin PCF:69 ; Antithrombic PAL:339 ; Antitumor 10 uM; Antitumor (Bladder) JNM7:51 ; Antitumor (Breast) JNM7:51 ; Antitumor (Colon) JAF45:4505 ; Antitumor (Lung) PMID10918203 ; Antitumor (Ovary) JNM7:51 ; Antitumor (Skin) 20 uM BO2 ; Antitumor-Promoter PAM ; Antiviral IC50=10 uM; Apoptotic 20-60 uM; ATPase-Inhibitor NIG ; Bacteristat 10 mg/ml QRNM(SUMMER):91 ; Bradycardiac KCH ; Calmodulin-Antagonist PAM ; cAMP-Phosphodiesterase-Inhibitor PAM ; Cancer-Preventive 525 ; Candidicide PMID10857921 ; Capillariprotective M11 ; Carcinogenic 40,000 ppm (diet) mus NIG ; Catabolic AFR27:173 ; COMT-Inhibitor QRNM1997:293 ; Copper-Chelator PR14:93 ; COX-2-Inhibitor <40 uM BO2 ; Cyclooxygenase-Inhibitor PCF:49 ; Cytotoxic ED50=70 ug/ml PM56(6):677 IC82=100 ug/ml PM57:A113 ; Deiodinase-Inhibitor JNM1:10 ; Diaphoretic? LRN-DEC90 ; Differentiator 5.5 uM BO2 ; Estrogenic 10% genistein B02 ; Fungicide PMID10857921 ; Glucosyl-Transferase-Inhibitor ID50=120 ug/ml JAF48:5666 ; Hemostat KCH ; Hepatomagenic 5,000 ppm (diet) rat PCF ; Hepatoprotective FT67:200 ; HIV-RT-Inhibitor IC50=<1 ug/ml JNP53(5):1239 ; Hypoglycemic 100 mg/kg orl rat JE27:243 ; Inotropic PMID10404425 ; Insulinogenic PAM ; Juvabional 438 ; Larvistat 8,000 ppm diet 438 ; Lipoxygenase-Inhibitor IC11=1.25 mM JAF38:688 IC50=0.1-5 uM DFN:154 ; MAO-A-Inhibitor QRNM1997:293 ; Mast-Cell-Stabilizer DUKE1992B ; Metal-Chelator (Copper) PR14:93 ; MMP-9-Inhibitor 20 uM BO2 ; Mutagenic HG22:27 ; NADH-Oxidase-Inhibitor BJP3:10 ; Neuroprotective 5-25 uM PMID11030720 ; Ornithine-Decarboxylase-Inhibitor <10 uM; P450-Inducer 5 uM FNF ; P450-Inhibitor 50-100 uM FNF ; Pesticide DUKE1992B ; Phospholipase-Inhibitor BJP3:10 ; Prostaglandin-Synthesis-Inhibitor 40 ug/ml PR11:281 ; Protein-Kinase-C-Inhibitor PCF:14 ; PTK-Inhibitor 0.4-24 uM BO2 ; Quinone-Reductase-Inducer 13 uM 6 uM CLE120:213 ; Teratologic DUKE1992B ; Topoisomerase-I-Inhibitor IC50=12.8 ug/ml IC50=42 uM BO2 ; Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml IC50=23-40 uM BO2 ; Tumorigenic 0.1% diet orl rat/yr 505 ; Tyrosine-Kinase-Inhibitor EMP6:170 ; Vasodilator; Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/ml CPB38:1772

QUERCITRIN Leaf: DUKE1992A
ACE-Inhibitor IC50=0.67 mM/ K25469 ; Aldose-Reductase-Inhibitor 0.1-100 uM 0.5-4 ug/ml IC50=2 uM CPB38:2733 IC50=64 uM rat SPJ4:45 IC55=0.1 uM PM56(3):257 IC55=0.15 uM; Antiarrhythmic DUKE1992B ; Antibacterial JBH ; Anticataract PM239:1986 ; Antiedemic KCH ; Antifeedant IC52=<1,000 ppm diet 438 ; Antiflu AYL ; Antihemorrhagic JBH ; Antihepatotoxic; Antiherpetic EMP5:198 ; Antiinflammatory KCH ; Antimutagenic ID50=2-5 nM PCF ; Antioxidant IC50=120 uM PC27:972 ; Antipurpuric DUKE1992B ; Antispasmodic JE26:76 ; Antistaphylococcic 0.412% HG40:24 ; Antithrombogenic DUKE1992B ; Antitumor DUKE1992B ; Antiulcer JBH ; Antiviral; Cancer-Preventive 525 ; Cardiotonic DUKE1992B ; Choleretic LAF ; CNS-Depressant DUKE1992B ; Cyclooxygenase-Activator 200 uM HH2 ; Detoxicant LAF ; Diuretic KCH ; Dye M11 ; Hemostat JBH ; Hepatotonic DUKE1992B ; Hypoglycemic EMP6:189 ; Hypotensive DUKE1992B ; Insectiphile JBH ; MAO-A-Inhibitor QRNM1997:293 ; MAO-Inhibitor HG40:12 ; Paralytic DUKE1992B ; Pesticide DUKE1992B ; Vasopressor JE26:76

RESIN Seed: DUKE1992A
No activity reported.

RUTIN Leaf: DUKE1992A
Aldose-Reductase-Inhibitor 100 uM 4 ug/ml SKN43:99 ; Allelochemic SN149:389 ; Antiapoplectic DUKE1992B ; Antiatherogenic LAF ; Antibacterial JBH ; Anticancer JAF47:397 ; Anticapillary-Fragility 20-100 mg orl man M7 ; Anticataract DUKE1992B ; Anticlastogen JAF48:1738 ; Anticonvulsant KCH ; AntiCVI 270 mg/man/day; Antidementia BRU ; Antidermatitic BIS ; Antidiabetic CPB38:297 ; Antiedemic 270 mg/day/or man; Antierythemic DUKE1992B ; Antifeedant 450 ; Antiglaucomic 60 mg/day WER ; Antihematuric DUKE1992B ; Antihemorrhoidal; Antihepatotoxic TOX ; Antiherpetic EMP5:198 ; Antihistaminic DUKE1992B ; Antihypertensive KCH ; Antiinflammatory 20 mg/kg DUKE1992B ; Antimalarial IC50=>100 ug/ml JE15:204 ; Antimutagenic ID50=2-5 nM PCF ; Antinephritic DUKE1992B ; Antioxidant IC28=30 ppm PCF IC50=120 uM PC27:972 ; Antipurpuric DUKE1992B ; Antiradicular 9 x quercetin; Antispasmodic; Antisunburn PM61:510 ; Antithrombogenic DUKE1992B ; Antitrypanosomic 100 mg/kg PM57:A44 ; Antitumor; Antitumor-Promoter; Antivaricose; Antiviral; cAMP-Phosphodiesterase-Inhibitor PAM ; Cancer-Preventive 525 ; Capillariprotective M11 ; Catabolic AFR27:173 ; Estrogenic? EMP6:189 ; Hemostat KCH ; Hepatomagenic 20,000 ppm (diet) rat PCF ; Hypocholesterolemic KCH ; Hypotensive LAF ; Insecticide TOX ; Insectiphile JBH ; Juvabional 382 ; Larvistat IC95=4,000-8,000 ppm diet 438 ; Lipoxygenase-Inhibitor IC75=2.5 mM JAF38:688 ; Mutagenic EMP6:189 ; Myorelaxant EMP6:189 ; Oviposition-Stimulant JBH ; Pesticide DUKE1992B ; Radioprotective JAF48:1738 ; Sunscreen PM61:510 ; Topoisomerase-II-Inhibitor IC50=1 ug/ml AAC41:992 ; Vasopressor DUKE1992B

SALANNIN Seed: DUKE1992A
Antifeedant RAA ; Antimalarial IC50=50 ug/mL PR4(1):33 ; Insectifuge 382 ; Pesticide DUKE1992B

SALANNOLIDE Plant: DUKE1992A
No activity reported.

SCOPOLETIN Plant: DUKE1992A
Aldose-Reductase-Inhibitor IC50=6.2 ug/ml cow CPB43:1385 ; Allelochemic IC89=2 mM 438 ; Analgesic PM56(6):595 ; Antiarrhythmic IWU ; Antiasthmatic DUKE1992B ; Antibacterial JBH ; Antibronchoconstrictor IWU ; Anticholinergic KCH ; Antiedemic DUKE1992B ; Antifeedant 382 ; Antihepatotoxic BIS ; Antiinflammatory ED 1-10 ug/ear PM56(6):504 ; Antileukotrienogenic PM56(6):595 ; Antimutagenic MAB ; Antioxidant PH2 ; Antiprostaglandin RWG27 ; Antiseptic FT1990:503 ; Antispasmodic; Antitumor 2.9 ug/ml DUKE1992B ; Bronchorelaxant KCH ; Cancer-Preventive 525 ; Cholagogue WIC ; Choleretic KCH ; CNS-Depressant KCH ; CNS-Stimulant WBB ; Cytotoxic MAB ; Fungicide 2 mM BIOSIS'96 ; Hepatoprotective WIC ; Herbicide JBH ; Hypoglycemic EMP6:165 ; Hypotensive FT#3:141.1986 ; Musculotropic WIC ; Myorelaxant WOI ; Pesticide DUKE1992B ; Phytoalexin PC29(6):1789 ; Phytohormonal JBH ; Uterosedative 411

STEARIC-ACID Fruit 79,650 - 81,000 ppm DUKE1992A
5-Alpha-Reductase-Inhibitor PMID10830511 ; Cosmetic JBH ; FLavor FEMA 2-4,000 ARC ; Hypocholesterolemic GAS ; Lubricant JBH ; Perfumery ARC ; Propecic PMID10830511 ; Suppository JBH

SUGIOL Bark: DUKE1992A
Aldose-Reductase-Inhibitor CPB45:1306

SULFUR Seed 1,921 ppm; DUKE1992A
Acarifuge DUKE1992B ; Antiacne M29 ; Antiarthritic WER ; Antidandruff M29 ; Antigrey M29 ; Antiosteoarthritic WER ; Antiseborrheic M29 ; Antiseptic M29 ; Comedogenic M29 ; Keratolytic M29 ; Laxative M29 ; Parasiticide M29 ; Pesticide DUKE1992B ; Scabicide M29

TANNIN Stem Bark 60,000 ppm; DUKE1992A
Anthelminthic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

VEPININ Seed: DUKE1992A
No activity reported.

VILASANIN Leaf: DUKE1992A
No activity reported.

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
450: Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134.
505: Jim Duke's personal files.
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
AAC41:992: Bernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
AAK: Atal and Kapur, 1982
ABEL1999: Jim Duke's personal files
ABS1: Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982.
AFR27:173: Jim Duke's personal files
AFR27:180: Jim Duke's personal files
AHP156: Jim Duke's personal files
ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.
AYL: Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
B02: Jim Duke's personal files
BIOSIS'96: Jim Duke's personal files
BIS: Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp. Note: English translation of Wichtl, 1984,1989).
BJP3:10: Jim Duke's personal files
BO2: Jim Duke's personal files
BRU: Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
CLE120:213: Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
COX:50: Jim Duke's personal files
CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
CPB38:1051: Jim Duke's personal files
CPB38:1772: Chem. & Pharm. Bull. 38: 1772.
CPB38:2733: Terashima, S., Shimizu, M., Nakayama, H., Ishikura, M., et al. 1990. Studies on Aldose Reductase Inhibitors from Medicinal Plant of "Sinfito," Potentilla candicans, and Further Synthesis of Their Related Compounds. Chem. Pharm. Bull 38(10):2733-2736, 1990
CPB38:297: Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990.
CPB38:3086: Seki, T., Toeda, C., Kawaguchi, T., Juni, K., Sugibayashi, K., and Morimoto, Y. 1990. Enhanced Transdermal Delivery of Zidovudine in Rats and Human Skin. Chem. Pharm. Bull. 38(11): 3086-3089, 1990.
CPB38:774: Yasukawa, K., Takido, M., Takeuchi, M., Sato, Y., Nitta, K., and Nakagawa, S. 1989. Inhibitory Effects of Flavonol Glycosides on 12-O-Tetradecanoylphorbol-13-acetate-Induced Tumor Promotion. Chem. Pharm. Bull. 38(3): 774-776, 1990.
CPB43:1385: Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
CPB45:1306: Tezuka, Y., Kasimu, R., Basnet, P., Namba, T., Kadota, S. 1997. Aldose Reductase Inhibitory Constituents of the Root of Salvia miltiorhiza Bunge. Chem Pharm Bull, 45(8): 1306-1311.
CPT59:62: Jim Duke's personal files
DAS: Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
DFN:154: Jim Duke's personal files
DFN:160: Jim Duke's personal files
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EMP1:53: Economic & Medicinal Plant Research, 1: 53.
EMP5:198: Economic & Medicinal Plant Research, 5: 198.
EMP5:199: Economic & Medicinal Plant Research, 5: 199.
EMP5:225: Economic & Medicinal Plant Research, 5: 225.
EMP5:333: Economic & Medicinal Plant Research, 5: 333.
EMP5:363: Economic & Medicinal Plant Research, 5: 363.
EMP6:165: Economic & Medicinal Plant Research, 6: 165
EMP6:170: Economic & Medicinal Plant Research, 6: 170.
EMP6:189: Economic & Medicinal Plant Research, 6: 189.
FAC: Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp.
FNF: Father Nature's Farmacy: The aggregate of all these three-letter citations.
FT#3:141.1986: Jim Duke's personal files
FT1990:503: Jim Duke's personal files
FT1990:508: Jim Duke's personal files
FT5:1990: Fitoterapia No.5-1990.
FT63(1):3: Jim Duke's personal files
FT63(3):197: Jim Duke's personal files
FT67:200: Jim Duke's personal files
FT67:548: Jim Duke's personal files
FT68(4):291: Jim Duke's personal files
GAS: Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
HG22:14: HerbalGram No. 22 - Spring 1990, page 14.
HG22:27: Jim Duke's personal files
HG22:31: Jim Duke's personal files
HG40:12: Jim Duke's personal files
HG40:24: Jim Duke's personal files
HH2: Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
IWU: Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
JAF37:1364.1989: Jim Duke's personal files
JAF38:688: Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
JAF45:4505: Jim Duke's personal files
JAF47:397: Jim Duke's personal files
JAF48:1738: Jim Duke's personal files
JAF48:5666: Jim Duke's personal files
JAFC37:1365: Jim Duke's personal files
JAFC48:220: Jim Duke's personal files
JBC8:211: Oliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JCN70:1040: Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
JE15:204: Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
JE26:74: Jim Duke's personal files
JE26:76: Jim Duke's personal files
JE26:80: Jim Duke's personal files
JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
JE28:221: Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
JE32:175: Jim Duke's personal files
JIM127:546: Jim Duke's personal files.
JMF2:227: Journal of Medicinal Food 2: 227.1999.
JMF2:235: Journal of Medicinal Food 2: 235.1999.
JNM1:10: Jim Duke's personal files.
JNM7:51: Jim Duke's personal files
JNP52:922: Jim Duke's personal files
JNP53(5):1239: Nakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
JNP54:142: Garcia, J., Morin,* C., Nyasse, B., Sondengam, B-L., Tchouankeu, J-C., and Tsamo, E. Complete Structural Assignments Of An Ergosterol Derivative From Entandrophragma utile. Journal of Natural Products, 54(1): 136-142, 1991.
JNP58:217: Constantinou, A., Mehta, R., Runyan, C., Rao, K., Vaughan, A., Moon, R. 1995. Flavonoids as DNA Topoisomerase Antagonists and Poisons: Structure-Activity Relationships. J Natural Products, 58: 217-225.
JNP59:205: Jim Duke's personal files
JNP59:987: Jim Duke's personal files
JNP60(9):884: Jim Duke's personal files
JNU: Jim Duke's personal files
K25469: Jim Duke's personal files
KCH: Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
LRN-DEC90: Lawrence Review of Natural Products, Dec-90.
LS55:1061: Life Sciences 55: 1061.
M&R495: Jim Duke's personal files
M11: Merck 11th Edition
M29: Martindale's 29th
M30: Martindale's 30th
M7: Merck 7th Ed.
MAB: Mills, Simon and Bone, Kerry. 2,000. Phytotherapy. Churchill Livinston, Edinburgh.
MAR: Martindale's 28th
MED: Medline (post 1990 searches filed in my computer)
MPT: Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
OMM: Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
P&T78:143: Jim Duke's personal files
PAL:339: Jim Duke's personal files
PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
PC27:972: Jim Duke's personal files
PC29(5):1667: Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
PC29(6):1789: Jim Duke's personal files
PC33:557: Okamura, H., Mimura, A., Yakou, Y., Niwano, M., and Takahara, Y. 1992. Antoxidant Activity of Tannins and Flavonoids in Eucalyptus rostrata. Phytochemistry. 33(3): 557-561. 1993.
PCF: Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
PCF:14: Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
PCF:49: Jim Duke's personal files
PCF:51: Jim Duke's personal files
PCF:69: Phenolic Compounds in Food and Their Effects on Health, 69.
PH2: Jim Duke's personal files
PJB1(2):287: Jim Duke's personal files
PM239:1986: Jim Duke's personal files
PM2:143: Jim Duke's personal files
PM2:145: Jim Duke's personal files
PM2:146: Jim Duke's personal files
PM56(2):171: Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
PM56(3):257: Jim Duke's personal files
PM56(3):258: Jim Duke's personal files
PM56(6):504: Jim Duke's personal files
PM56(6):595: Jim Duke's personal files
PM56(6):677: Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
PM56(6):695: Planta Medica, 56(6): 695, 1990.
PM57:A110: Planta Medica, 57: A110, 1991.
PM57:A113: Planta Medica, 57: A113, 1991.
PM57:A131: Planta Medica, 57: A131, 1991.
PM57:A133: Schussler, M., Fricke, U., Nikolov, N., and Holzl, J. 1991. Comparison of the Flavonoids Occurring in Crataegus species and Inhibition of 3',5'-Cyclic Adenosine Monophosphate Phosphodiesterase. Plant Medica 57: Suppl Issue 2. p.A-133.
PM57:A43: Planta Medica, 57: A43, 1991.
PM57:A44: Planta Medica, 57: A44, 1991.
PM61:510: Jim Duke's personal files
PMID10404425: Jim Duke's personal files
PMID10673981: Jim Duke's personal files
PMID10813558: Jim Duke's personal files
PMID10830511: Jim Duke's personal files
PMID10857921: Jim Duke's personal files
PMID10918203: Jim Duke's personal files
PMID10923837: Jim Duke's personal files
PMID11020457: Jim Duke's personal files
PMID11030720: Jim Duke's personal files
PMP23:193: Kumar, P., Dixit*, V.P., and Khanna, P. Antifertility Studies of Kaempferol: Isolation and Identification from Tissue Culture of some Medicinally Important Plant Species. Plantes medicinales et phytotherapie, 23: 193-201, 1989.
PMP23:60: Jim Duke's personal files
POP:153: Jim Duke's personal files
POP:270: Jim Duke's personal files
PR11:281: Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
PR13:102: Meckes, M., Calzada, F., Tapia-Contreras, A., Cedillo-Rivera, R. 1999. Antiprotozoal Properties of Helianthemum glomeratum. Phytotherapy Research, 13(2): 102-105.
PR14:93: Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
PR4(1):33: Jim Duke's personal files
PR4(1):34: Jim Duke's personal files
PR4(5):201: Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
PR4:33: Jim Duke's personal files
PS131:95: Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
PS75:161: Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
QJC28:155: Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
QRNM(SUMMER):91: Jim Duke's personal files
QRNM1997:293: Jim Duke's personal files
RAA: Rizk, A.F.M. and Al-Nowaihi, A.S., The Phytochemistry of the Horticultural Plants of Qatar, Scientific and Applied Research Centre, University of Qatar.
RR21:85: Rastitel'nye Resursy, 21: 85.
RWG122: Jim Duke's personal files
RWG125: Jim Duke's personal files
RWG27: Jim Duke's personal files
RWG29: Jim Duke's personal files
SKN43:99: Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
SN146:421: Science News, 146: 421.
SN149:389: Jim Duke's personal files
SPJ4:45: Al-Khalil, S. 1996. Inhibition of Lens Alkaloids Reductase by Protopine Alkaloids. Saudi Pharm J, 4(1): 45-47.
SYN-X: Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
TIH14:223: Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
TOX: Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
V&D: Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
WBB: Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp.
WER: Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
WIC: Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
WOI: ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
ZUL: Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
ZZZ18:623: Mao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 18:07:13 EDT 2002

Please send questions and comments to:

James A. Duke (E-Mail: JimDuke@cpcug.org)
or
Stephen M. Beckstrom-Sternberg (E-Mail: SteveBS@nhgri.nih.gov)

Please send technical questions and comments to:

WebMaster (E-Mail: WebMaster@ars-grin.gov)

The USDA does not recommend self diagnosis or self medication. Please see the disclaimer for more information.