Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Chenopodium ambrosioides L. (Chenopodiaceae) -- Epazote, Wormseed


Chemicals

ALPHA-PINENE Plant 440 - 4,800 ppm DUKE1992A
Allelochemic DUKE1992B ; Allergenic M&R523 ; Antibacterial RIE12:5 ; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antiinflammatory IJO15(4):194 ; Antiviral EMP5:195 ; Cancer-Preventive 525 ; Coleoptophile DUKE1992B ; Expectorant MIK ; FLavor FEMA 15-150 ARC ; Herbicide IC50=30 uM TOX ; Insectifuge 50 ppm; Insectiphile JSPR22:141 ; Irritant JBH ; Perfumery ARC ; Pesticide DUKE1992B ; Sedative LRN-JUN90 ; Spasmogenic CAN ; Tranquilizer LRN-JUN90

ARITASONE Plant 9 - 1,400 ppm DUKE1992A
No activity reported.

ASCARIDOLE Leaf 185 - 18,000 ppm DUKE1992A
Analgesic CPB41:1309 ; Ancylostomicide DUKE1992B ; Anthelminthic JBH ; Antiflatulent DUKE1992B ; Carcinogenic CRC ; Carminative DUKE1992B ; Fungicide DUKE1992B ; Nematicide M11 ; Pesticide DUKE1992B ; Sedative CPB41:1309 ; Vermifuge DUKE1992B

ASCORBIC-ACID Leaf 110 - 1,020 ppm DUKE1992A
Acidulant FEMA 6,000 ARC ; Aldose-Reductase-Inhibitor SYN-X ; Analgesic 5-10 g day; Antiaggregant SYN-X ; Antiaging 2,000 mg/day SYN-X 400 mg/day; Antiarthritic 1 g day WER ; Antiasthmatic 1,000 mg/day WER ; Antiatherosclerotic PAM ; Antibacterial DAS ; Anticataract 350 mg/day WER 400 mg/day SYN-X ; Anticold 1-2 g/man/day MAR ; AntiCrohn's 50-100 mg/day/orl/man M29 ; Antidecubitic 500 mg/man/2x/day MAR ; Antidepressant 2,000 mg/day WER ; Antidiabetic SYN-X ; Antidote (Aluminum) EMP6:189 ; Antidote (Cadmium) DAS ; Antidote (Lead) DAS ; Antidote (Paraquat) MAR ; Antieczemic 3.5-5 g/day WER ; Antiedemic 1 g/man/day DAS ; Antiencephalitic DAS ; Antigingivitic PAM ; Antiglaucomic 2 g/day WER ; Antihemorrhagic 1 g/man/day DAS ; Antihepatitic 2-6 g/man/day DAS ; Antihepatotoxic EMP6:189 ; Antiherpetic 1-5 g/day WER ; Antihistaminic 2 g/day orl man; Antiinfertility 1 g/day WER ; Antiinflammatory PAM ; Antilepric 1.5 g/man/day MAR ; Antimeasles DAS ; Antimigraine M29 ; Antimutagenic EMP6:235 ; Antinitrosic 1 g/man/day MAR ; Antiobesity 1 g 3 x day WER ; Antiorchitic DAS ; Antiosteoarthritic 1 g 2 x day WER ; Antiosteoporotic 500 mg day; Antioxidant 100 ppm DUKE1992B ; Antiparkinsonian 1 g 2 x day WER ; Antiparotitic DAS ; Antiperiodontitic WER ; Antipneumonic PAM ; Antipodriac DAS ; Antipoliomyelitic DAS ; Antipyretic EMP6:189 ; Antiradicular SYN-X ; Antiscorbutic 10 mg/man/day MAR ; Antiseptic 4-8 g/day SYN-X MIC=3.3-217 mg/ml MAR ; Antishingles DAS ; Antisyndrome-X 1-4 g/day SYN-X ; Antitumor (Lung) NR54:S71 ; Antiulcer WER ; Antiviral 1-5 g/day; Apoptotic 1-10 mM BO2 ; Asthma-preventive 1,000 mg/day/orl PAM ; Beta-Glucuronidase-Inhibitor 1.5 g/day/man BO2 ; Cancer-Preventive 525 ; Cold-preventive 1-2 g/day DAS ; Collagenic BO2 ; Detoxicant DUKE1992B ; Diuretic 700 mg/man/orl DUKE1992B ; Fistula-Preventive PAM ; Hypocholesterolemic 300-1,000 mg/day DAS ; Hypoglycemic SYN-X ; Hypotensive 1,000 mg/man/day SNE137:292 ; Immunostimulant SYN-X ; Interferonogenic PAM ; Lithogenic DAS ; Mucolytic 1 g/woman/day MAR ; Pesticide DUKE1992B ; Uricosuric 4 g/man/day DAS ; Urinary-Acidulant M29 ; Vulnerary PAM

ASH Leaf 24,000 - 166,000 ppm DUKE1992A
No activity reported.

BETA-CAROTENE Leaf 35 - 165 ppm DUKE1992A
Allergenic M&R610 ; Androgenic? PAM ; Antiacne PAM ; Antiaging DUKE1992B ; Antiasthmatic PAM ; Anticancer JNU ; Anticarcinomic PAM ; Anticoronary 50 mg/man/2 days CMR3/4/91:16 ; Antihyperkeratotic; Antiichythyotic PAM ; Antileukoplakic PAM ; Antilupus 150 mg/man/day/2 mos MAR ; Antimastitic PAM ; Antimutagenic EMP6:235 ; Antioxidant PAM ; Antiozenic DUKE1992B ; Antiphotophobic 30-300 mg man/day M29 ; Antipityriasic PAM ; AntiPMS JAFC34:409 ; Antiporphyric 30-300 mg/man/day MAR ; Antiproliferant JNU ; Antipsoriac PAM ; Antiradicular PAM ; Antistress DAS ; Antitumor HSC25:1495 ; Antiulcer 12 mg/3x/day/man/orl PAM ; Antixerophthalmic DAS ; Cancer-Preventive 22 ppm 505 ; Colorant JBH ; Immunostimulant 180 mg/man/day/orl PAM ; Interferon-Synergist PJB1(2):264 ; Mucogenic PAM ; Phagocytotic PAM ; Prooxidant 20 ug/g JAF44:2096 ; Thymoprotective PAM ; Ubiquiot JBH

BUTYRIC-ACID Plant: DUKE1992A
Anticancer WER ; Antitumor WER ; Apoptotic BOI ; Bruchifuge 382 ; Nematistat 880 ug/ml NIG ; Pesticide DUKE1992B

CALCIUM Leaf 3,000 - 21,000 ppm DUKE1992A
Antiallergic 500 mg/day; Antianxiety DAS ; Antiatherosclerotic WER ; Antidepressant DAS ; Antidote (Aluminum) DAS ; Antidote (Lead) DAS ; Antihyperkinetic DAS ; Antiinsomniac DAS ; Antiosteoporotic 500 mg day WER ; Antiperiodontitic 750 mg day WER ; AntiPMS 1 g day WER ; Antitic DAS ; Hypocholesterolemic 500 mg day WER ; Hypotensive 1 g/day WER

CARBOHYDRATES Leaf 76,000 - 524,000 ppm DUKE1992A
No activity reported.

D-CAMPHOR Plant: DUKE1992A
No activity reported.

EO Fruit 1,830 - 25,000 ppm DUKE1992A Leaf 2,000 - 3,000 ppm DUKE1992A
No activity reported.

FAT Leaf 7,000 - 48,000 ppm DUKE1992A Seed 25,000 - 92,000 ppm CRC
No activity reported.

FERULIC-ACID Fruit: DUKE1992A
Allelopathic JCE17:865 ; Analgesic ACM:69 ; Antiaggregant CPB38:1620 ; Antiallergic LAF ; Antiarrhythmic PJB1(2):270 ; Antibacterial JBH ; Anticancer (Colon) PAL:335 ; Anticancer (Forestomach) PAL:335 ; Anticancer (Liver) PAL:335 ; Anticancer (Skin) PAL:335 ; Anticarcinogenic JAF45:661 ; Antidysmenorrheic CPB38:1623 ; Antiestrogenic JBH ; Antihepatotoxic JBH ; Antiherpetic JAR10:7 ; Antiinflammatory PCF:19 ; Antimitotic JBH ; Antimutagenic PCF:18 ; Antineoplastic (Stomach) NR11:S120 ; Antinitrosaminic PCF:18 ; Antioxidant 3,000 uM PC27:973 IC51=200 ppm PCF:221 ; Antiserotonin JBH ; Antispasmodic LAF ; Antithrombic LAF ; Antitumor JBH ; Antitumor (Colon) PAL:335 ; Antitumor (Forestomach) PAL:335 ; Antitumor (Liver) PAL:335 ; Antitumor (Skin) PAL:335 ; Antitumor-Promoter IC46=10 uM CR48:5941 ; Antiviral V&D ; Arteriodilator CPB38:1620 ; Cancer-Preventive 525 ; Candidicide JBH ; Cardiac CPB38:1620 ; Cholagogue PHZ46:156 ; Choleretic 411 ; Fungicide NIG ; Hepatoprotective MAB ; Hepatotropic DUKE1992B ; Herbicide AB68:195 ; Hydrocholerectic JBH ; Hypolipidemic NR11:S120 ; Immunostimulant EMP1:124 ; Insectifuge EB48:111 ; Metal-Chelator PCF:25 ; Ornithine-Decarboxylase-Inhibitor PCF:19 ; Pesticide DUKE1992B ; Phagocytotic; Preservative M11 ; Prostaglandigenic RWG27 ; Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mM YHH25:412 ; Sunscreen CMR9/10/92 ; Uterosedative 30-100 mg/kg ivn rat CPB38:1620

FIBER Leaf 13,000 - 90,000 ppm DUKE1992A
Antidiabetic DUKE1992B ; Antiobesity DUKE1992B ; Antitumor PAM ; Antiulcer PAM ; Cancer-Preventive 525 ; Cardioprotective DUKE1992B ; Hypocholesterolemic DUKE1992B ; Hypotensive 10 g/man/day/orl PAM ; Laxative DUKE1992B

GERANIOL Plant: DUKE1992A
Allergenic; Anthelminthic MAD ; Antibacterial MIC=400 ug/ml JAF41:1103 ; Anticancer (Pancreas) IC50=265 uM LIP32:151 ; Anticariogenic MIC=400 ug/ml JAF41:1103 ; Antimelanomic IC50=150 uM/l JN127:668 ; Antiseptic 7 x phenol W&W ; Antispasmodic JEO2:185 ; Antitumor JAF43:2144 ; Antitumor (Pancreas) IC50=265 uM LIP32:151 ; Ascaricide MAD ; Cancer-Preventive 525 ; Candidicide DUKE1992B ; CNS-Stimulant HHB ; Embryotoxic DUKE1992B ; Emetic 3 x ipecac LRN-SEP97 ; Expectorant MAD ; FLavor FEMA 1-10 ARC ; Fungicide IC93=2 mM 438 ; Herbicide IC100-2,000 uM TOX ; Insectifuge 50 ppm JSPR22:141.1986 ; Insectiphile M11 ; Nematicide IC86=100 ug/ml NIG MLC=1,000 ug/ml SZ44:183 ; Perfumery M11 ; Pesticide DUKE1992B ; Sedative; Trichomonicide LD100=300 ug/ml FT67:279

IRON Plant 52 ppm; DUKE1992A
Antiakathisic M29 ; Antianemic M29 ; Anticheilitic DAS ; Antimenorrhagic 100 mg/day/wmn/orl PAM

KILOCALORIES Leaf 420 - 900 /kg DUKE1992A
No activity reported.

L-PINOCARVONE Plant 1,040 - 11,400 ppm DUKE1992A
No activity reported.

LEUCINE Plant: DUKE1992A
Antiencephalopathic M29 ; Essential JBH

LIMONENE Plant: DUKE1992A
AChE-Inhibitor 453 ; Allelochemic JAF45:3276 ; Allergenic (1/20th carene) M&R521 ; Antiacetylcholinesterase IC22-26=1.2 mM JAF45:677 ; Antialzheimeran? 453 ; Antibacterial RIE12:5 ; Anticancer AEM401:131 ; Antifeedant JAF45:3276 ; Antiflu EMP5:195 ; Antilithic M29:1064 ; Antimutagenic EMP6:235 ; Antiseptic JAF44:2802 ; Antispasmodic ED50=0.197 mg/ml FT59:465 ; Antitumor; Antitumor (Breast) AEM401:131 ; Antitumor (Pancreas) AEM401:131 ; Antitumor (Prostate) AEM401:131 ; Antiviral; Cancer-Preventive 525 ; Candidistat JAF40:2330 ; Chemopreventive AEM401:131 ; Enterocontractant JAR4:22 ; Expectorant; FLavor PJB1(3):242 ; Fungiphilic JAF43:2283 ; Fungistat JAF40:2330 ; Herbicide IC50=45 uM TOX ; Insecticide 453 ; Insectifuge 382 ; Irritant; Nematicide IC=100 ug/ml NIG ; Ornithine-Decarboxylase-Inhibitor 750 mg/kg (diet) BO2 ; Pesticide DUKE1992B ; Photosensitizer RIN ; Sedative ED=1-32 mg/kg W&W

MALIC-ACID Fruit: DUKE1992A
Bacteristat DUKE1992B ; Bruchiphobe 382 ; Hemopoietic DUKE1992B ; Laxative? LRN-SEP91 ; Pesticide DUKE1992B ; Sialogogue M29

MENTHADIENE Plant: DUKE1992A
No activity reported.

METHYL-SALICYLATE Plant: DUKE1992A
Allergenic MAR ; Analgesic JE26:76 ; Antiinflammatory PM56(6):660 ; Antipyretic DUKE1992B ; Antiradicular JPP42:205 ; Antirheumatalgic MAR ; Antiseptic JAF44:2802 ; Cancer-Preventive 525 ; Carminative JE26:76 ; Counterirritant M11 ; Dentifrice ARC ; FLavor FEMA 70-8,000 ARC ; Insectifuge JCE20:2847 ; Perfumery ARC ; Pesticide DUKE1992B

MYRCENE Plant: DUKE1992A
ACE-Inhibitor 100 ug/ml K26575 ; Aldose-Reductase-Inhibitor TYK1992:95 ; Allergenic M&R154 ; Analgesic EMM18:28 ; Antibacterial DUKE1992B ; Antimutagenic EMM18:28 ; Antinociceptive 10-20 mg/kg ipr mus JPP42:877 20-40 mg/kg scu mus JPP42:877 ; Antioxidant JA6(4):33 ; Antispasmodic PM&T20:213.1986 ; FLavor FEMA 0.5-9 ARC ; Fungicide TOX ; Insectifuge DUKE1992B ; Irritant ZEB ; Perfumery JBH ; Pesticide DUKE1992B

NIACIN Leaf 5 - 40 ppm DUKE1992A
Allergenic WER ; Antiacrodynic DUKE1992B ; Antiallergic 50 mg/2x/day WER ; Antiamblyopic DUKE1992B ; Antianginal DUKE1992B ; Antichilblain JBH ; Anticonvulsant 3 g/day WER ; Antidermatitic DAS ; Antidysphagic DUKE1992B ; Antiepileptic WER ; Antihistaminic 50 mg/2x/day WER ; Antihyperactivity 1.5-6 g/day WER ; Antiinsomnic 1 g/day WER ; AntiMeniere's JAD ; Antineuralgic DUKE1992B ; Antiparkinsonian 100 mg/day WER ; Antipellagric DAS ; Antiscotomic DUKE1992B ; Antispasmodic 100 mg/2x/day WER ; Antivertigo DUKE1992B ; Cancer-Preventive 525 ; Hepatoprotective DUKE1992B ; Hypoglycemic DUKE1992B ; Hypolipidemic RWG17 ; Sedative PAM ; Serotoninergic PAM ; Vasodilator M29

P-CYMENE Leaf 365 - 4,400 ppm DUKE1992A
Analgesic MAR ; Antiacetylcholinesterase IC40=1.2 mM JAF45:677 ; Antibacterial JE26:74 ; Antiflu DUKE1992B ; Antirheumatalgic MAR ; Antiviral DUKE1992B ; FLavor FEMA 12-250 ARC ; Fungicide TOX ; Herbicide IC50=50 uM TOX ; Insectifuge HH3 ; Irritant ZEB ; Laxative ZEB ; Pesticide DUKE1992B ; Sedative ZEB ; Trichomonicide LD100=50 ug/ml FT67:279

P-CYMOL Plant 730 - 8,000 ppm DUKE1992A
No activity reported.

PHOSPHORUS Leaf 520 - 3,585 ppm DUKE1992A
Antiosteoporotic DAS ; Immunostimulant DAS ; Osteogenic DAS

PROTEIN Fruit 156,000 ppm; DUKE1992A Leaf 38,000 - 262,000 ppm DUKE1992A
No activity reported.

RIBOFLAVIN Leaf 3 - 19 ppm DUKE1992A
Antiarabiflavinotic 2-10 mg/orl day MAR ; Anticarpal-Tunnel 50 mg/day WER ; Anticataract 15 mg/day WER ; Anticheilitic DUKE1992B ; Antidecubitic DUKE1992B ; Antiglossitic DAS ; Antikeratitic DUKE1992B ; Antimigraine DUKE1992B ; Antipellagric DUKE1992B ; Antiphotophobic DAS ; Cancer-Preventive 525

SAFROLE Plant: DUKE1992A
Anesthetic JE26:79 ; Antiaggregant IC50=110 uM JE29:184 ; Antibacterial JE26:79 ; Anticonvulsant JBH ; Antiseptic M11 ; Calcium-Antagonist IC50=57 uM gpg IC50=58 uM LAB58 ; Cancer-Preventive 525 ; Carcinogenic M11 ; Carminative JE26:80 ; CNS-Depressant JBH ; CNS-Stimulant HHB ; Controlled HG20:15 ; Cytochrome-P450-Inducer CAN ; Cytochrome-P488-Inducer CAN ; DNA-Binder JBH ; Hepatocarcinogenic CAN ; Hepatoregenerative CRC ; Hepatotoxic M29 ; Hypothermic JBH ; Irritant RIN ; Mutagenic AHP152 ; Nematicide MLC=1 mg/ml SZ44:183 ; Neurotoxic RJH ; Pediculicide M11 ; Perfumery M11 ; Pesticide DUKE1992B ; Psychoactive RJH ; Tremorigenic AFR27:212

SAPONINS Root 25,000 ppm; DUKE1992A
Antihepatomic NR54:S71 ; Antimutagenic NR54:S71 ; Antitumor (Lung) NR54:S71 ; Antitumor (Ovary) NR54:S71 ; Immunomodulator NR54:S71

SODIUM Leaf 10 - 70 ppm DUKE1992A
Hypertensive DAS

SPINASTEROL Plant: DUKE1992A
No activity reported.

TARTARIC-ACID Plant: DUKE1992A
Acidifier JBH ; Additive ARC ; Antioxidant Synergist M29 ; FLavor FEMA 500-10,000 ARC ; Irritant ZEB ; Sequestrant ARC

TERPINENE Plant: DUKE1992A
No activity reported.

TERPINYL-ACETATE Plant 75 ppm; DUKE1992A
Antibacterial RIE12:5 ; FLavor FEMA 1-260 ARC ; Insectifuge 382 ; Perfumery ARC ; Pesticide DUKE1992B

TERPINYL-SALICYLATE Plant 75 ppm; DUKE1992A
No activity reported.

THIAMIN Leaf 0.6 - 4 ppm DUKE1992A
Analgesic 1-4 g/day WER ; Antialcoholic DUKE1992B ; Antialzheimeran 100-3,000 mg day WER ; Antianorectic JBH ; Antibackache 1-4 g day WER ; Antiberiberi DUKE1992B ; Anticardiospasmic DUKE1992B ; Anticolitic DUKE1992B ; Antidecubitic DUKE1992B ; Antideliriant DUKE1992B ; Antiencephalopathic M29 ; Antifatigue JBH ; Antigastritic JBH ; Antiheartburn DUKE1992B ; Antiherpetic DUKE1992B ; Antimigraine DUKE1992B ; Antimyocarditic DUKE1992B ; Antineuralgic WER ; Antineurasthenic DUKE1992B ; Antineuritic DUKE1992B ; Antineuropathic 50 mg WER ; Antipoliomyelitic DUKE1992B ; Insectifuge 75-150 mg/man/day MAR ; Pesticide DUKE1992B

TRIACONTYL-ALCOHOL Plant: DUKE1992A
No activity reported.

TRIMETHYLAMINE Plant: DUKE1992A
Antioxidant PC27:974

UREASE Plant: DUKE1992A
No activity reported.

VANILLIC-ACID Fruit: DUKE1992A
Aldose-Reductase-Inhibitor 100 uM/l PHM1:145 ; Anthelminthic JBH ; Antibacterial 1.5-15 mg/ml 452 ; Anticancer JAF47:397 ; Antifatigue; Antiinflammatory JBH ; Antioxidant IC21=30 ppm; Antiradicular 7 x quercetin JAF47:397 ; Antisickling PM56(6):681 ; Antitumor JAF47:397 ; Antitumor-Promoter JAF47:397 ; Ascaricide DUKE1992B ; Cancer-Preventive 525 ; Choleretic DUKE1992B ; Immunosuppressant RWG29 ; Laxative MPI ; Pesticide DUKE1992B ; Ubiquiot JBH

WATER Leaf 855,000 ppm; DUKE1992A
No activity reported.

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
452: Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
453: Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
505: Jim Duke's personal files.
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
AB68:195: Angewandte Botanik 68(5/6)=1994. Page 195.
ACM:69: Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
AEM401:131: Jim Duke's personal files
AFR27:212: Jim Duke's personal files
AHP152: Jim Duke's personal files
ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.
BO2: Jim Duke's personal files
BOI: Jim Duke's personal files
CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
CMR3/4/91:16: Jim Duke's personal files
CMR9/10/92: Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
CPB38:1620: Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
CPB38:1623: Jim Duke's personal files
CPB41:1309: Jim Duke's personal files
CR48:5941: Cancer Research, 48: 5941.
CRC: CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses
DAS: Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EB48:111: Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
EMM18:28: Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
EMP1:124: Economic & Medicinal Plant Research, 1: 124.
EMP5:195: Economic & Medicinal Plant Research, 5: 195.
EMP6:189: Economic & Medicinal Plant Research, 6: 189.
EMP6:235: Economic & Medicinal Plant Research, 6: 235.
FT59:465: Fitoterapia No.59-1984.
FT67:279: Jim Duke's personal files
HG20:15: HerbalGram No. 20, page 15.
HH3: Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
HHB: List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
HSC25:1495: Simon, P.W. Carrots and Other Horticultural Crops as a Source of Provitamin A Carotenes. HortScience, 25(12): 1495, 1990.
IJO15(4):194: Internat. J. Oriental Med. 15(4): 194, 1990+
JA6(4):33: Jim Duke's personal files.
JAD: Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
JAF40:2330: Jim Duke's personal files
JAF41:1103: Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
JAF43:2144: Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147.
JAF43:2283: J. Agric. Food Chem. 43: 2283.
JAF44:2096: Jim Duke's personal files
JAF44:2802: Jim Duke's personal files
JAF45:3276: Jim Duke's personal files
JAF45:661: Jim Duke's personal files
JAF45:677: Jim Duke's personal files
JAF47:397: Jim Duke's personal files
JAFC34:409: Jim Duke's personal files
JAR10:7: Jim Duke's personal files
JAR4:22: J. Aromatherapy 4: 22.
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JCE17:865: Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
JCE20:2847: Hardie, J., Isaacs, R., Pickett,* J.A., Wadhams, L.J., and Woodcock, C.M. 1994. Methyl Salicylate and (-)-(1R,5S)-Myrtenal are Plant-Derived Repellents for Black Bean Aphid, Aphis Fabae Scop. (Homoptera: Aphididae). J. of Chemical Ecology, 20(11):2847.
JE26:74: Jim Duke's personal files
JE26:76: Jim Duke's personal files
JE26:79: Jim Duke's personal files
JE26:80: Jim Duke's personal files
JE29:184: Janssens, J., Laekeman, G.M., Pieters, L.A.C., Totte, J., Herman, A.G., and Vlietinck, A.J. 1990. Nutmeg Oil: Identification and Quantitation of its Most Active Constituents as Inhibitors of Platelet Aggregation. J.of Ethnopharmacology, 29: 179-188, 1990.
JEO2:185: Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
JN127:668: Jim Duke's personal files
JNU: Jim Duke's personal files
JPP42:205: O'Connell, M.J., Webster, N.R. 1989. Hyperoxia and salicylate metabolism in rats. J. Pharm. Pharmacol. 42: 205-206, 1990.
JPP42:877: Rao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
JSPR22:141: J. Stored. Prod. Res., 22:141, 1986.
JSPR22:141.1986: Jim Duke's personal files
K26575: Jim Duke's personal files
LAB58: Jim Duke's personal files
LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
LIP32:151: Jim Duke's personal files
LRN-JUN90: Lawrence Review of Natural Products, Jun-90.
LRN-SEP91: Lawrence Review of Natural Products, Sep-91.
LRN-SEP97: Lawrence Review of Natural Products, Sep-97.
M&R154: Jim Duke's personal files
M&R521: Jim Duke's personal files
M&R523: Jim Duke's personal files
M&R610: Jim Duke's personal files
M11: Merck 11th Edition
M29: Martindale's 29th
M29:1064: Jim Duke's personal files
MAB: Mills, Simon and Bone, Kerry. 2,000. Phytotherapy. Churchill Livinston, Edinburgh.
MAD: Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
MAR: Martindale's 28th
MIK: Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
MPI: =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp Note: (2 vols so far).
NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
NR11:S120: Jim Duke's personal files
NR54:S71: Jim Duke's personal files
PAL:335: Jim Duke's personal files
PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
PC27:973: Jim Duke's personal files
PC27:974: Jim Duke's personal files
PCF:18: Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
PCF:19: Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
PCF:221: Jim Duke's personal files
PCF:25: McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
PHM1:145: Jim Duke's personal files
PHZ46:156: Pharmazie, 46: 156, 1991.
PJB1(2):264: Jim Duke's personal files
PJB1(2):270: Jim Duke's personal files
PJB1(3):242: Jim Duke's personal files
PM&T20:213.1986: Jim Duke's personal files.
PM56(6):660: Planta Medica, 56(6): 660, 1990.
PM56(6):681: Planta Medica, 56(6): 681, 1990.
RIE12:5: Revista Itiliana Eppos, 12: 5, 1994.
RIN: Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
RJH: R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
RWG17: Jim Duke's personal files
RWG27: Jim Duke's personal files
RWG29: Jim Duke's personal files
SNE137:292: Jim Duke's personal files.
SYN-X: Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
SZ44:183: Shoyakugaku Zasshi, 44: 183.
TOX: Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
TYK1992:95: Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
V&D: Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
WER: Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
YHH25:412: Xu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 18:21:34 EDT 2002

Please send questions and comments to:

James A. Duke (E-Mail: JimDuke@cpcug.org)
or
Stephen M. Beckstrom-Sternberg (E-Mail: SteveBS@nhgri.nih.gov)

Please send technical questions and comments to:

WebMaster (E-Mail: WebMaster@ars-grin.gov)

The USDA does not recommend self diagnosis or self medication. Please see the disclaimer for more information.