Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Krameria triandra R. & P. (Krameriaceae) -- Rhatany


No activity reported.

Anticoagulant DUKE1992B ; Cancer-Preventive 525 ; Cardiotonic DUKE1992B ; Vasoconstrictor AYL

Allelochemic IC100=1 mM 438 ; Antiaggregant IC94=200 ug/ml PR13:597 ; Antianaphylactic; Antibacterial MIC=>1,000 ug/ml; Anticomplementary 1/2 aspirin PM57:A48 ; Antidiabetic 30 mg/kg rat; AntiEBV EMP6:189 ; Antihepatitic V&D ; AntiHIV EC50=2 ug/ml POP:270 ; Antihyperglycemic; Antiinflammatory; Antileukemic IC50=>10 ug/ml; Antilipoperoxidant PR13:597 ; Antimutagenic; Antioxidant 2.5 x Vit. E BO2 IC50=6.3 ug/ml CPB38:1049 ; Antiperoxidant JBH ; Antiviral; Cancer-Preventive 525 ; Cardiotonic DUKE1992B ; Choline-Sparing AFR27:149 ; Hepatotropic DUKE1992B ; Hypocholesterolemic AFR27:149 ; Hypoglycemic DUKE1992B ; Insulinogenic EMP6:170 ; Lipoxygenase-Inhibitor IC50=140 uM PCF IC97=5 mM JAF38:688 ; Pancreatogenic DUKE1992B ; Peroxynitrite-Scavenger IC50=0.181 ug/ml JAF48:5768 ; Pesticide DUKE1992B ; Propecic PH2 ; Xanthine-Oxidase-Inhibitor IC50=>40

No activity reported.

No activity reported.

GUM Root: DUKE1992A
No activity reported.

No activity reported.

No activity reported.

No activity reported.

Antialopecic PH2 ; Antiatherosclerotic PH2 ; AntiCVI 100 mg/day/man BO2 ; Antiedemic 400 mg/kg/day orl rat; Antihistaminic BO2 ; Antiischemic PH2 ; Antioxidant 5 x Vit. E BO2 >Vit E-succinate; Antiperiodontal PAM ; Antiplaque PAM ; Antiretinopathic PH2 ; Antiseptic HG40:12 ; Antistroke 200 mg/kg orl rat BO2 ; Antitumor PH2 ; Antiviral HG40:12 ; Beta-Glucuronidase-Inhibitor IC50=1 uM BO2 ; Capillariprotective PH2 ; Cardioprotective PH2 ; Collagenase-Inhibitor BO2 ; Collagenic BO2 ; Deodorant LAF ; Elastase-Inhibitor IC50=~4 uM BO2 ; Hepatoprotective PH2 ; Hyaluronidase-Inhibitor IC50+=50-80 uM BO2 ; Ornithine-Decarboxylase-Inhibitor BO2 ; Propecic PH2 ; Vasodilator HG40:12

ACE-Inhibitor IC30-90=150-333 ug/ml LAB54 ; Antiallergic IJO16:204 ; Antianaphylactic OPC ; Antibacterial PM56(6):577 ; Antibiotic DUKE1992B ; Antiedemic 2 x phenylbutazone; Antierythemic OPC ; Antiexudative APP16:50 ; Antigastritic OPC ; Antiherpetic EMP5:197 ; Antihistaminic OPC ; AntiHIV DUKE1992B ; Antioxidant OPC ; Antiradicular OPC ; Antiviral EMP5:197 ; Beta-Adrenergic Receptor Blocker 10 uM PC44:441 ; Beta-Glucuronidase-Inhibitor IC50=1.1 uM/l ARZ44:592 ; Capillariprotective IC50=1-80 uM/l ARZ44:592 ; Capillaritonic APP16:50 ; Collagenase-Inhibitor IC50=38 uM/l ARZ44:592 ; Deodorant LAF ; Elastase-Inhibitor IC50=4.24 uM/l ARZ44:592 ; Hyaluronidase-Inhibitor IC50=80 uM/l; Pesticide DUKE1992B ; Sunscreen; Xanthine-Oxidase-Inhibitor IC50=2.4 uM/l ARZ44:592 IC50=>40 CPB38:1225

No activity reported.

Antiarrhythmic ACM:407 ; Antiasthmatic DUKE1992B ; Antibacterial PR4(5):198 ; Anticlastogen PMID9025787 ; Antihepatotoxic JBH ; Antiherpetic DUKE1992B ; Antiinflammatory JBH ; Antiischemic JBH ; Antimutagenic PMID9025787 ; Antiophidic EMP5:363 ; Antioxidant ABC53:519 ; Antiperoxidant IC50=>100 uM PM57:A54 ; Antiradicular JAF45:1039 ; Antispasmodic EC50=4.6-17 uM PR4(2):73 ; Antitussive ACM:200 ; Antiviral JAF45:1039 ; Fungicide 500 ug/ml 438 ; Immunostimulant EMP1:124 ; Pesticide DUKE1992B ; Phagocytotic EMP1:124 ; Prostaglandigenic RWG27 ; Secretogogue CAN ; Ubiquiot JBH

No activity reported.

RHATANY-TANNIC-ACID Root 80,000 - 180,000 ppm DUKE1992A Root Bark 420,000 ppm; DUKE1992A
No activity reported.

Absorbent M29 ; Antidote (Iodine) JBH ; Antinesidioblastosic M29 ; Emollient M29 ; Poultice M29

No activity reported.

Anthelminthic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

WAX Root: DUKE1992A
No activity reported.


438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ABC53:519: Kikuzaki, H. and Nakatani, N. 1988. Structure of a New Antioxidative Phenolic Acid from Oregano (Origanum vulgare L.). Agric. Biol. Chem. 53: 519-524.
ACM:200: Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
ACM:407: Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 407.
AFR27:149: Singleton, V.L. 1981. Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods. Advances in Food Research 27: 149-217.
AHP156: Jim Duke's personal files
APP16:50: Jim Duke's personal files
ARZ44:592: Jim Duke's personal files
AYL: Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
BO2: Jim Duke's personal files
CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
CPB38:1051: Jim Duke's personal files
CPB38:1225: Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EMP1:124: Economic & Medicinal Plant Research, 1: 124.
EMP5:197: Economic & Medicinal Plant Research, 5: 197.
EMP5:363: Economic & Medicinal Plant Research, 5: 363.
EMP6:170: Economic & Medicinal Plant Research, 6: 170.
EMP6:189: Economic & Medicinal Plant Research, 6: 189.
HG22:14: HerbalGram No. 22 - Spring 1990, page 14.
HG40:12: Jim Duke's personal files
IJO16:204: Jim Duke's personal files
JAF38:688: Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
JAF45:1039: Jim Duke's personal files
JAF47:397: Jim Duke's personal files
JAF48:5768: Jim Duke's personal files
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JE26:74: Jim Duke's personal files
JNP59:205: Jim Duke's personal files
LAB54: Jim Duke's personal files
LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
M29: Martindale's 29th
OPC: Jim Duke's personal files
PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
PC44:441: Zhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
PCF: Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
PH2: Jim Duke's personal files
PM56(6):577: Jim Duke's personal files
PM57:A48: Jim Duke's personal files
PM57:A54: Planta Medica, 57: A54, 1991.
PMID9025787: Jim Duke's personal files
POP:270: Jim Duke's personal files
PR13:597: Jim Duke's personal files
PR4(2):73: Ortiz de Urbina, J.J., Martin, M.L., Sevilla, M.A., Montero, M.J., Carron, R., and San Roman, L. Antispasmodic Activity on Rat Smooth Muscle of Polyphenol Compounds Caffeic and Protocathechic Acids. Phytotherapy Research 4(2): 73, 1990.
PR4(5):198: Lamikanra, A., Ogundaini, A.O., and Ogungbamila*, F.O. Antibacterial Constituents of Alchornea cordifolia Leaves. Phytotherapy Research 4(5): 198.
RWG27: Jim Duke's personal files
RWG29: Jim Duke's personal files
V&D: Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 17:05:18 EDT 2002

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James A. Duke (E-Mail:
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