Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Petiveria alliacea (Phytolaccaceae) -- Anamu, Guinea Hen Leaf, Mucura

Chemicals

BENZALDEHYDE Root: TRA

Allergenic M&R594 ; Anesthetic DUKE1992B ; Antibacterial LAF337 ; Anticancer ARO95:16 ; Antipeptic DUKE1992B ; Antiseptic DUKE1992B ; Antispasmodic DUKE1992B ; Antitumor ARO95:16 ; Candidicide LAF337 ; FLavor FEMA 150-800 ARC ; Immunostimulant ARO95:16 ; Insecticide LAF ; Insectifuge 50 ppm JSPR22:141 ; Motor-Depressant BVC:162 ; Narcotic M11 ; Nematicide MLC=1 mg/ml SZ44:183 ; Pesticide DUKE1992B ; Sedative BVC:162 ; Tyrosinase-Inhibitor ID50=0.82 mM JAF47:4574 ID50=820 uM JAF46:1268 ID50=87 ug/ml JAF46:1268

BENZOIC-ACID Root: TRA

Allergenic MAR ; Anesthetic DUKE1992B ; Antibacterial 33-1,250 ppm DUKE1992B ; Antiotitic MAR ; Antipyretic DUKE1992B ; Antiseptic M29 ; Choleretic JBH ; Expectorant DUKE1992B ; FLavor FEMA 250 ARC ; Fungicide M11 ; Insectifuge 382 ; Pesticide DUKE1992B ; Phytoalexin JBH ; Uricosuric DUKE1992B ; Vulnerary JE26:82

BENZYL-2-HYDROXYETHYL-TRISULFIDE Leaf: HHB

Antibiotic HHB

COUMARIN Root: HHB

Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 11% inhibition) CPB43:1385 ; Allelochemic IC100=2 mM 438 ; Analgesic ZEB ; Antiaggregant DUKE1992B ; Antiandrogenic PM56(6):671 ; Antibrucellosic JPP42:194 ; Anticancer (Kidney) 400-7,000 mg/day MAB ; Anticancer (Prostate) MAB ; Antidiuretic CAN117 ; Antiedemic CPB38:2283 ; Antiesherichic JBH ; Antiinflammatory CPB38:2283 ; Antilymphedemic MAB ; Antimelanomic 50 mg/day; Antimetastatic 50 mg/man/day MAB ; Antimitotic IJP33:7 ; Antimononuccleotic MAB ; Antimutagenic EMP6:235 ; Antimycoplasmotic MAB ; Antipsittacotic MAB ; Antipsoriac IJP33:7 ; Antitoxoplasmotic MAB ; Antitumor 50 mg/day; Antitumor (GI) JAR9(4):182 ; Antitumor (Kidney) 400-7,000 mg/day MAB ; Antitumor (Prostate) MAB ; Bacteristat JBH ; Bruchiphobe DUKE1992B ; Cancer-Preventive 5-25 ug/ml PM1987:526 ; Carcinogenic 200 mg/kg orl mus MAB ; Cardiodepressant FEL ; Cardiotonic FEL ; Chemopreventive JAR9(4):182 ; DME-Inhibitor IC50=57.5 uM ACM:134 ; Emetic DUKE1992B ; Estrogenic CAN ; Fungicide JBH ; Hemorrhagic JBH ; Hepatotoxic 0.8-1.71 mM/kg orl rat 100 mg/kg dog ARO95:21 2,500 ppm diet ARO95:21 ; Hypnotic EB44:68.1990 ; Hypoglycemic 250-1,000 mg/kg orl EMP6:165 ; Immunostimulant; Juvabional 382 ; Larvistat JBH ; Lymphocytogenic 100 mg/day JPP42:194 ; Lymphokinetic PH2 ; Narcotic FEL ; Ovicide DUKE1992B ; Pesticide DUKE1992B ; Phagocytotic PM56(6):671 ; Piscicide JBH ; Rodenticide JBH ; Sedative EB44:68.1990

ISOARBORINOL Plant: JFM

No activity reported.

ISOARBORINOL-ACETATE Plant: JFM

No activity reported.

ISOARBORINOL-CINNAMATE Plant: JFM

No activity reported.

ISOTHIOCYANATES Seed: WOI

No activity reported.

POLYPHENOLS Leaf: TRA

Anthelminthic JNP59:205 ; Antibacterial JE26:74 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antiophidic EMP5:363 ; Antioxidant IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor JNP59:205 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

SENFOL Leaf: HHB

No activity reported.

TANNINS Leaf: TRA

No activity reported.

TRITHIOLANIACINE Root: TRA

Antiseptic GMJ ; Insectifuge GMJ

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.

438: Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.

ACM:134: Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

ARO95:16: Jim Duke's personal files

ARO95:21: Jim Duke's personal files

BVC:162: Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC

CAN: Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.

CAN117: Jim Duke's personal files

CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.

CPB38:1051: Jim Duke's personal files

CPB38:2283: Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug "Alhucema" (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.

CPB43:1385: Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EB44:68.1990: Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.

EMP5:363: Economic & Medicinal Plant Research, 5: 363.

EMP6:165: Economic & Medicinal Plant Research, 6: 165

EMP6:235: Economic & Medicinal Plant Research, 6: 235.

FEL: Jim Duke's personal files

GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.

HG22:14: HerbalGram No. 22 - Spring 1990, page 14.

HHB: List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.

IJP33:7: Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.

JAF46:1268: Jim Duke's personal files

JAF47:4574: Jim Duke's personal files

JAR9(4):182: Jim Duke's personal files

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:74: Jim Duke's personal files

JE26:82: Jim Duke's personal files

JFM: Morton, J.F., Major Medicinal Plants. 1977. Atlas of Medicinal Plants of Middle America. Bahamas to Yucatan. 1981.

JNP59:205: Jim Duke's personal files

JPP42:194: Gawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.

JSPR22:141: J. Stored. Prod. Res., 22:141, 1986.

LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

LAF337: Jim Duke's personal files

M&R594: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

MAB: Mills, Simon and Bone, Kerry. 2,000. Phytotherapy. Churchill Livinston, Edinburgh.

MAR: Martindale's 28th

PH2: Jim Duke's personal files

PM1987:526: Gawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.

PM56(6):671: Planta Medica, 56(6): 671, 1990.

RWG29: Jim Duke's personal files

SZ44:183: Shoyakugaku Zasshi, 44: 183.

TRA: Tramil

WOI: ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.

ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

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