Dr. Duke's
Phytochemical and Ethnobotanical Databases
Chemicals and their Biological Activities in:
Scoparia dulcis (Scrophulariaceae)
Chemicals
- BETULINIC-ACID
Plant 500 ppm;
JAD
Root:
JAD
-
Anticarcinomic JBH
; AntiHIV EC50=2.0 ug/ml JNP61:1090
IC50=6.5 ug/ml JNP57:243
; Antiinflammatory PM61:9
; Antimalarial IC50=19-26 ug/ml PR13:115
; Antimelanomic NYT3/28/95
; Antiplasmodial PR13:115
; Antitumor JBH
; Antiviral JNP57:243
; Cytotoxic 50-100 ppm BPCC
; Prostaglandin-Synthesis-Inhibitor 200 ug/ml PC48:495
IC50=101 uM YHH30:621
References
- BPCC:
Biosyn. Prod. Cancer Chemotherapy (Petit et al)
- JAD:
Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
- JBH:
Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
- JNP57:243:
Fujioka, T., Kashiwada, Y., et al. Anti-AIDS Agents 11. Betulinic Acid and Platanic Acid as Anti-HIV Principles From Syzigium claviflorum, and the Anti-HIV Activity of Structurally Related Triterpenoids. Journal of Natural Products, 57(2): 243-247, 1994.
- JNP61:1090:
Kashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
- NYT3/28/95:
New York Times, 3/28/95.
- PC48:495:
Dunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
- PM61:9:
Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
- PR13:115:
Jim Duke's personal files
- YHH30:621:
Huang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
ppm = parts per million
tr = trace
Phytochemical Database, USDA - ARS - NGRL,
Beltsville Agricultural Research Center,
Beltsville, Maryland
Thu May 16 16:21:08 EDT 2002
Please send questions and comments to:
- James A. Duke (E-Mail:
JimDuke@cpcug.org)
- or
- Stephen M. Beckstrom-Sternberg
(E-Mail:
SteveBS@nhgri.nih.gov)
Please send technical questions and comments to:
-
WebMaster (E-Mail:
WebMaster@ars-grin.gov)
The USDA does not recommend self diagnosis or self medication.
Please see the disclaimer
for more information.