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Ayapana Powder Ayapana triplinervis1 Pound (16 oz) Buy Now
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Purchase a one pound package of Raintree's sustainably harvested pure ayapana leaf powder - rich in active and beneficial phytochemicals that occur naturally in this plant. This plant has been milled into a fine powder which is suitable to stuff into capsules or to prepare your own teas, tinctures or extracts. Raintree's ayapana has been sustainably wild-harvested in the Amazon Rainforest (without any pesticides or fertilizers).
Traditional Uses:* as a stomachic for digestive problems (nausea, vomiting, stomachaches); for coughs, sore throat, colds, and bronchitis; for ulcers (mouth, skin, gastric); for cuts, scrapes, and wounds; for tumors
For more information about ayapana please refer to the Database File for Ayapana in the Tropical Plant Database. For general information on Raintree's available bulk plants and sustainable harvesting practices, please refer to Main Page for Bulk Plants.
This bulk one pound package retails for $28.00. Purchase Ayapana Powder Now
Print a PDF Ayapana Brochure
Ingredients: 100% pure ayapana leaves (Ayapana triplinervis). No binders, fillers or additives are used. This is a wild harvested plant—grown naturally in the Peruvian Amazon without any pesticides or fertilizers.
Suggested Use: This plant is best prepared as an infusion (tea): Use one teaspoon of powder for each cup of water. Pour boiling water over herb in cup and allow to steep 10 minutes. Strain tea (or allow settled powder to remain in the bottom of cup) and drink warm. It is traditionally taken in 1 cup dosages, twice daily.
For more complete instrutions on preparing herbal infusions see the Methods for Preparing Herbal Remedies Page.
Contraindications:
Ayapana leaves contain naturally occurring coumarins. Coumarin has an anti-coagulant and blood thinning effect and is a precursor to coumadin drugs. Consult with your physician before taking this plant if you are taking coumadin drugs or if coumadin anticoagulant type drugs are contraindicated for your condition.
Drug Interactions: Ayapana may enhance or increase the effect of blood-thinning medications.
RELATED PRODUCTS:
Ayapana can be found in these Raintree products:
Ayapana Tech Report -- A Technical Plant Data Report is available for ayapana.
Third-Party Published Research*
This Raintree product has not been the subject of any clinical research.
All available third-party research on ayapana can be found at PubMed/Medline.
A partial listing of the published research on ayapana is shown below:
Blood-Thinning Actions:
Bose, P. K., et al. “Haemostatic agents. Part II. Experiments with ayapanin and ayapin.” Nature 1937; 139: 515.
Bose. P.K., et al. “Haemostatic agents. Part I. Experiments with avapanin and ayapin.” Annals Biochem. Expt. Med. 1931; 1: 311-316.
da Souza, J. A., et al. “Blood coagulation activity of the Ayapin, (6,7-metilen-dioxy-coumarin) obtained from Alomia fastigiata Benth (Compositae).” Rev. Fac. Farm. Odontol. Araraquara. 1974 Jul-Dec; 8(2): 123-7.
Adaval, S. C., et al. “Effect of vitamin K 3 and ayapana on blood coagulation of normal buffalo calves.” Indian J. Physiol. Pharmacol. 1970 Jul; 14(3): 207.
Cytotoxic & Anticancerous Actions:
Riveiro, M., et al. "Toward establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells." Bioorg. Med. Chem. 2009 Sep 15; 17(18): 6547-59.
Kawase, M., et al. “Coumarin derivatives with tumor-specific cytotoxicity and multidrug resistance reversal activity.” In Vivo. 2005 Jul-Aug; 19(4): 705-11.
Watanabe, J., et al. “Coumarin and flavone derivatives from estragon and thyme as
inhibitors of chemical mediator release from RBL-2H3 Cells.” Biosci. Biotechnol. Biochem. 2005; 69(1): 1-6.
Riveiro, M., et al. "Induction of cell differentiation in human leukemia U-937 cells by 5-oxygenated-6,7-methylenedioxycoumarins from Pterocaulon polystachyum." Cancer Lett. 2004 Jul 16; 210(2): 179-88.
Scio, E., et al. "Diterpenes from Alomia myriadenia (Asteraceae) with cytotoxic and trypanocidal activity." Phytochemistry. 2003 Nov;64(6): 1125-31.
Antimicrobial Actions:
Stein, A., et al. "Antifungal activity of some coumarins obtained from species of Pterocaulon (Asteraceae)." J. Ethnopharmacol. 2006 Aug 11; 107(1): 95-8.
Prsts, E., et al. "Antifungal activity of a new phenolic compound from capitulum of a head rot-resistant sunflower genotype." J. Chem. Ecol. 2007 Dec; 33(12): 2245-53.
Jelager, L., et al. “Antibacterial and antifungal activity of medicinal plants of Mauritius.” Pharmaceutical Biol. 1998; 36:153-161.
Gupta, M., et al. “Antimicrobial activity of Eupatorium ayapana.” Fitoterapia. 2002; 73 (2):168-170.
Verpoorter, R., et al. “Medicinal plants of Surinam. IV. Antimicrobial activity of some medicinal plants.” J. Ethnopharmacol. 1987; 21: 315-318.
Chaurasia, S. C., et al. “Activity of essential oils of three medicinal plants against various pathogenic and nonpathogenic fungi. Indian J. Hosp. Pharm. 1978; 15 pp. 139-141.
Sharma, S. K., et al. “The antifungal activity of some essential oils.” Indian Drugs Pharm Ind.. 1979; (14) 1: 3-6.
Garg, S. C., et al. “Studies on the essential oil from the flowers of Eupatorium triplinerve.” Indian Perfum 1993; 37 (4): 318-323.
Kokate, C. K., et al. “Pharmacological studies on the essential oil of Eupatorium triplinerve. I. Effects on the central nervous system and antimicrobial activity.” Flavour. 1971; 2 (3): 177-180.
Insecticidal and Antifeedant Actions:
Vera, N., et al. "Toxicity and synergism in the feeding deterrence of some coumarins on Spodoptera frugiperda Smith (Lepidoptera: Noctuidae)." Chem. Biodivers. 2006 Jan; 3(1) :21-6.
Facknath, S., et al. “Response of three important insect pests of horticultural crops in Mauritius to extracts of Ayapana triplinervis.” Journal of Applied Entomology 1999b.
Lalljee B., et al. “Biocidal potential of Eupatorium ayapana extracts”. Book of Abstracts. Symposium on Integrated Pest Management for Sustainable Crop Production, 2-4 Dec. 1997, IARI, New Delhi, India. page 64.
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* The statements contained herein have not been evaluated
by the Food and Drug Administration.
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not intended to treat, cure, mitigate or prevent any disease.
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Last updated 3-20-2010
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